Amino-terminal FLAG-tag octapeptide alters oligomerization of expressed surfactant protein-A

konka-chemical

UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a possible therapeutic goal

Background: N-end rule ubiquitination pathway is thought to be disrupted in lots of ailments, together with most cancers. UBR5, an E3 ubiquitin ligase, is mutated and/or overexpressed in human lung most cancers cells suggesting its pathological function in most cancers.

Strategies: We decided expression of UBR5 protein in a number of lung most cancers cell traces and human affected person samples. Utilizing immunoprecipitation adopted by mass spectrometry we decided the UBR5 interacting proteins. The affect of lack of UBR5 for lung adenocarcinoma cell traces was analyzed utilizing cell viability, clonogenic assays and in vivo xenograft fashions in nude mice.

Extra Western blot evaluation was carried out to evaluate the lack of UBR5 on downstream signaling. Statistical evaluation was finished by one-way ANOVA for in vitro research and Wilcoxon paired t-test for in vivo tumor volumes.

Outcomes: We present variability of UBR5 expression ranges in lung adenocarcinoma cell traces and in major human affected person samples. To realize higher perception into the function that UBR5 might play in lung most cancers development we carried out unbiased interactome analyses for UBR5.

Knowledge point out that UBR5 has a variety of interacting protein companions which might be recognized to be concerned in important mobile processes similar to DNA injury, proliferation and cell cycle regulation. We’ve got demonstrated that shRNA-mediated lack of UBR5 decreases cell viability and clonogenic potential of lung adenocarcinoma cell traces.

As well as, we discovered decreased ranges of activated AKT signaling after the lack of UBR5 in lung adenocarcinoma cell traces utilizing a number of technique of UBR5 knockdown/knockout. Moreover, we demonstrated that lack of UBR5 in lung adenocarcinoma cells leads to vital discount of tumor quantity in nude mice.

Conclusions: These findings exhibit that deregulation of the N-end rule ubiquitination pathway performs an important function within the etiology of some human cancers, and blocking this pathway by way of UBR5-specific inhibitors, might signify a singular therapeutic goal for human cancers.

konka-chemical
konka-chemical

QPCR Kit DNA Universal m - EACH

MOL6610 EACH
EUR 1258.76

Genorise® Universal DNA Mini Kit 50

GR101076 50
EUR 223

Genorise® Universal DNA Mini Kit 100

GR101076-100 100
EUR 357

Genorise® Universal DNA Mini Kit 200

GR101077 200
EUR 567

Genorise® Universal DNA Mini Kit 500

GR101077-500 500
EUR 1272

Methylamp Universal Methylated DNA Kit 

P-1011
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  • 20 Modifications
  • 10 Modifications
  • 20 Modifications

QPCR Kit DNA Universal f Mmix - EACH

MOL6608 EACH
EUR 1581.9

QPCR Kit DNA Universal m Mmix - EACH

MOL6612 EACH
EUR 1581.9

VAHTS Universal DNA Library Prep Kit for MGI

NDM607-01 24 rxn
EUR 879.6

VAHTS Universal DNA Library Prep Kit for MGI

NDM607-02 96 rxn
EUR 2563.2

Universal Solution for DNA isolation (GeDI)

E3760-01 25ml
EUR 30.52

Universal Solution for DNA isolation (GeDI)

E3760-02 100ml
EUR 95.92

VAHTS Universal DNA library Prep Kit for MGI V4

NDM610-01 24 rxns
EUR 235.2

VAHTS Universal DNA library Prep Kit for MGI V4

NDM610-02 96 rxns
EUR 880

VAHTS Universal DNA library Prep Kit for MGI V3

NDM607-00-6rxns 6 rxns
EUR 1.09

VAHTS Universal DNA library Prep Kit for MGI V3

NDM607-01-24rxns 24 rxns
EUR 304.66

VAHTS Universal DNA library Prep Kit for MGI V3

NDM607-02-96rxns 96 rxns
EUR 1139.05

GeneMATRIX UNIVERSAL DNA/RNA/Protein Purification Kit

E3597-01 25preps
EUR 81.75
Description: Kit for isolation of total DNA/RNA/Protein from the same biological sample(bacteria, tissue, plant, yeast, cell culture)

GeneMATRIX UNIVERSAL DNA/RNA/Protein Purification Kit

E3597-02 100preps
EUR 299.75
Description: Kit for isolation of total DNA/RNA/Protein from the same biological sample(bacteria, tissue, plant, yeast, cell culture)

Methylamp Universal Methylated DNA Preparation Kit

P-1019 40 µg
EUR 416.7

VAHTS Universal DNA Library Prep Kit for Illumina V3

ND607-01 24 rxn
EUR 529.2

VAHTS Universal DNA Library Prep Kit for Illumina V3

ND607-02 96 rxn
EUR 1686

VAHTS Universal DNA Library Prep Kit for Illumina V4

ND610-01 24 rxns
EUR 294

VAHTS Universal DNA Library Prep Kit for Illumina V4

ND610-02 96 rxns
EUR 1100

VAHTS Universal DNA Library Prep Kit for Ion Torrent

ND701-01 24 rxn
EUR 879.6

VAHTS Universal DNA Library Prep Kit for Ion Torrent

ND701-02 96 rxn
EUR 2563.2

VAHTS Universal DNA Library Prep Kit for Illumina V4

ND610-00-6rxns 6 rxns
EUR 1.09

VAHTS Universal DNA Library Prep Kit for Illumina V4

ND610-01-24rxns 24 rxns
EUR 304.44

VAHTS Universal DNA Library Prep Kit for Illumina V4

ND610-02-96rxns 96 rxns
EUR 1139.05

VAHTS Universal DNA Library Prep Kit for Illumina V4

ND610-03-24rxns 24 rxns
EUR 269.23

VAHTS Universal DNA Library Prep Kit for Illumina V4

ND610-04-96rxns 96 rxns
EUR 999.53

AFTSpin Universal Plant Fast DNA Extraction Kit

RK30111 50RXN
EUR 69

EpiMag High Throughput DNA Isolation Universal Kit

P-1022-96 96 Samples
EUR 227.7

EpiMag High Throughput DNA Isolation Universal Kit

P-1022 96 Samples
EUR 215

Universal-1

OD308-1PK 1 unit
EUR 2.65
Description: Universal-1

Universal-1

OD308R-1PK 1 unit
EUR 2.65
Description: Universal-1

VAHTS Universal DNA Library Prep Kit for Ion Torrent V2

ND702-01 24 rxns
EUR 294

VAHTS Universal DNA Library Prep Kit for Ion Torrent V2

ND702-02 96 rxns
EUR 1100

Universal Kit for DNA isolation with GeDI Solution

E3765-01 25preps
EUR 59.95

Universal Kit for DNA isolation with GeDI Solution

E3765-02 100preps
EUR 210.37

VAHTS Universal Pro DNA Library Prep Kit for MGI

NDM608-01 24 rxn
EUR 907.2

VAHTS Universal Pro DNA Library Prep Kit for MGI

NDM608-02 96 rxn
EUR 2740.8

VAHTS Universal Plus DNA Library Prep Kit for MGI

NDM617-01 24 rxn
EUR 988.8

VAHTS Universal Plus DNA Library Prep Kit for MGI

NDM617-02 96 rxn
EUR 2889.6

VAHTS Universal Pro DNA Library Prep Kit for Illumina

ND608-01 24 rxn
EUR 558

VAHTS Universal Pro DNA Library Prep Kit for Illumina

ND608-02 96 rxn
EUR 1858.8

VAHTS Universal Plus DNA Library Prep Kit for MGI V2

NDM627-01 24 rxns
EUR 312.5

VAHTS Universal Plus DNA Library Prep Kit for MGI V2

NDM627-02 96 rxns
EUR 1150

VAHTS Universal Plus DNA Library Prep Kit for MGI V2

NDM627-00-6rxns 6 rxns
EUR 1.09

VAHTS Universal Plus DNA Library Prep Kit for MGI V2

NDM627-01-24rxns 24 rxns
EUR 323.59

VAHTS Universal Plus DNA Library Prep Kit for MGI V2

NDM627-02-96rxns 96 rxns
EUR 1190.83

VAHTS Universal Plus DNA Library Prep Kit for Illumina

ND617-01 24 rxn
EUR 590.4

VAHTS Universal Plus DNA Library Prep Kit for Illumina

ND617-02 96 rxn
EUR 1926

Universal Holder

LBI10201 each
EUR 161.87

Hexa Universal-2

HX038-1PK 1 unit
EUR 2.51
Description: Hexa Universal-2

VAHTS Universal DNA Library Prep Kit for Illumina V3 (PCR-Free)

ND607-03 24 rxn
EUR 514.8

VAHTS Universal DNA Library Prep Kit for Illumina V3 (PCR-Free)

ND607-04 96 rxn
EUR 1624.8

Universal Platform

SS-300-U each
EUR 250

Universal Indicator

I013-100ML 1 unit
EUR 2.65
Description: Universal Indicator

Universal Indicator

I013-500ML 1 unit
EUR 9.01
Description: Universal Indicator

VAHTS Universal Plus DNA Library Prep Kit for Illumina V2

ND627-01 24 rxns
EUR 312.5

VAHTS Universal Plus DNA Library Prep Kit for Illumina V2

ND627-02 96 rxns
EUR 1150

VAHTS Universal Plus DNA Library Prep Kit for Illumina V2

ND627-00-6rxns 6 rxns
EUR 1.09

VAHTS Universal Plus DNA Library Prep Kit for Illumina V2

ND627-01-24rxns 24 rxns
EUR 323.59

VAHTS Universal Plus DNA Library Prep Kit for Illumina V2

ND627-02-96rxns 96 rxns
EUR 1190.83

Hexa Universal - 1

HX032-1PK 1 unit
EUR 2.51
Description: Hexa Universal - 1

Hexa Universal - 4

HX715-1PK 1 unit
EUR 2.51
Description: Hexa Universal - 4

Hexa Universal - 5

HX716-1PK 1 unit
EUR 2.51
Description: Hexa Universal - 5

Icosa Universal - 1

IC001-1PK 1 unit
EUR 9.32
Description: Icosa Universal - 1

Icosa Universal - 2

IC006-1PK 1 unit
EUR 9.32
Description: Icosa Universal - 2

Dodeca Universal -XI

DE026-1PK 1 unit
EUR 3.96
Description: Dodeca Universal -XI

Dodeca - Universal XV,

DE042-1PK 1 unit
EUR 3.96
Description: Dodeca - Universal XV,

Universal V1-Puck

M-CP-111-021 1 PUCK
EUR 350
Description: Universal V1-Puck

UNIVERSAL BEER AGAR

U21-100-10kg 10 kg
EUR 1828.8

UNIVERSAL BEER AGAR

U21-100-2kg 2kg
EUR 444

UNIVERSAL BEER AGAR

U21-100-500g 500 g
EUR 164.4

Dodeca Universal-I

DE001-1PK 1 unit
EUR 3.96
Description: Dodeca Universal-I

Dodeca Universal-V

DE013-1PK 1 unit
EUR 3.96
Description: Dodeca Universal-V

Dodeca Universal -XII

DE027-1PK 1 unit
EUR 3.96
Description: Dodeca Universal -XII

Dodeca Universal XIV

DE035-1PK 1 unit
EUR 3.96
Description: Dodeca Universal XIV

Universal WB Toolkit

KTD106-EN-each each Ask for price

Universal WB Toolkit

KTD106-EN-Null Null Ask for price

Universal WB Toolkit

KTD106-EN-20T 20 T
EUR 59
Description: Abbkine has developed a Universal WB Toolkit. After careful design and research, one-stop operation can meet the needs of routine WB experiments and obtain excellent experimental results.

Universal WB Toolkit

MBS9719335-20Tests 20Tests
EUR 195

Universal WB Toolkit

MBS9719335-5x20Tests 5x20Tests
EUR 885

Dodeca Universal-II

DE007-1PK 1 unit
EUR 3.96
Description: Dodeca Universal-II

Dodeca Universal-IV

DE012-1PK 1 unit
EUR 3.96
Description: Dodeca Universal-IV

Dodeca Universal-VI

DE014-1PK 1 unit
EUR 3.96
Description: Dodeca Universal-VI

Dodeca Universal-IX

DE017-1PK 1 unit
EUR 3.96
Description: Dodeca Universal-IX

Dodeca Universal- XIII

DE028-1PK 1 unit
EUR 3.96
Description: Dodeca Universal- XIII

Dodeca Universal-III

DE008-1PK 1 unit
EUR 3.96
Description: Dodeca Universal-III

Dodeca Universal-VII

DE015-1PK 1 unit
EUR 3.96
Description: Dodeca Universal-VII

APP Antibody (universal)

GWB-C298C6 0.1 ml Ask for price

Universal qPCR Mixture

QPCR1000-UNIV 4X1.25ml
EUR 331.44

NBS Universal Platform

SHA4070 EACH
EUR 708.93

NBS Universal Platform

SHA4232 EACH
EUR 388.8

NBS Universal Platform

SHA4256 EACH
EUR 476.61

NBS Universal Platform

SHA4272 EACH
EUR 756.04

NBS Universal Platform

SHA4290 EACH
EUR 1016.3

Universal Block Buffer

TBS5013 100 ml
EUR 60

Universal Basal Medium

cAP-01C 500ml
EUR 64.35

*Universal Liquid Medium

M1332-500G 1 unit
EUR 25.78
Description: *Universal Liquid Medium

Universal vessel holder

LBI10230 each
EUR 156.96

Universal platform - EACH

INC1112 EACH
EUR 1613.25

Universal Growth Medium

cAP-01B 500ml
EUR 89.1

Universal Heating System

LBI10501 each
EUR 11281.5

Universal Spring Platform

H1000-P-SP 1 PC
EUR 660.13

Universal Spring Platform

H1010-P-SP 1 each
EUR 697.83

Universal Attachment - EACH

MIX1320 EACH
EUR 322.65

Universal Coating Solution

MBS556488-20mL 20mL
EUR 310

Universal Coating Solution

MBS556488-5x20mL 5x20mL
EUR 1235

Universal Oven UN30 - EACH

OVE8314 EACH
EUR 1881.9

Universal Oven UN55 - EACH

OVE8316 EACH
EUR 2196.45

Universal Oven UN75 - EACH

OVE8318 EACH
EUR 2281.5

Universal Oven UF30 - EACH

OVE8332 EACH
EUR 2150.55

Universal Oven UF55 - EACH

OVE8334 EACH
EUR 2594.7

Universal Oven UF75 - EACH

OVE8336 EACH
EUR 2737.8

Universal Restriction Buffer

EN-300 5 x 1ml
EUR 22.7

Grant Universal Tray - EACH

BAT4622 EACH
EUR 353.7

Universal AC adapter - EACH

PIP3214 EACH
EUR 87.75

Universal Oven UN110 - EACH

OVE8320 EACH
EUR 2922.75

Universal Oven UN160 - EACH

OVE8322 EACH
EUR 3524.85

Universal Oven UN260 - EACH

OVE8324 EACH
EUR 4666.95

Universal Oven UN450 - EACH

OVE8326 EACH
EUR 6176.25

Universal Oven UN750 - EACH

OVE8328 EACH
EUR 8275.5

Universal Oven UF110 - EACH

OVE8338 EACH
EUR 3235.95

Universal Oven UF160 - EACH

OVE8340 EACH
EUR 4207.95

Universal Oven UF260 - EACH

OVE8342 EACH
EUR 5364.9

Universal Oven UF450 - EACH

OVE8344 EACH
EUR 7025.4

Universal Oven UF750 - EACH

OVE8346 EACH
EUR 9309.6

Universal Detachment Solution

AD002 100 ml
EUR 177.6

UNIVERSAL PREENRICHMENT BROTH

U21-101-10kg 10 kg
EUR 898.8

UNIVERSAL PREENRICHMENT BROTH

U21-101-2Kg 2 Kg
EUR 242.4

UNIVERSAL PREENRICHMENT BROTH

U21-101-500g 500 g
EUR 109.2

Universal Detachment Solution

MBS556489-100mL 100mL
EUR 185

Universal Detachment Solution

MBS556489-5x100mL 5x100mL
EUR 680

Ilford Universal Stop Bath

21956-500 500ml
EUR 73

Universal Spring Tray - EACH

BAT7177 EACH
EUR 336.15

PCR plate-foil universal

A28216 1x100 pcs
EUR 112.8

PCR plate-foil universal

A28216L 5x100 pcs
EUR 372

Universal Oven UF1060 - EACH

OVE8348 EACH
EUR 17192.25

MGI Universal Blockers-S

RK20278 4RXN
EUR 425.1

MGI Universal Blockers-D

RK20279 4RXN
EUR 425.1

PCV cap proteins fused with calreticulin expressed into polymers in Escherichia coli with excessive immunogenicity in mice

Background: Porcine circovirus kind 2 (PCV2) is the principle causative agent of porcine circovirus ailments (PCVDs) which causes large yearly financial losses within the swine business. Capsid protein (Cap) is the foremost structural protein of PCV2 that may induce a protecting immune response. Due to this fact, creating a novel and protected subunit vaccine towards PCV2 an infection is required.

Outcomes: On this examine, the Cap gene was sure to the truncated calreticulin (CRT) (120-250 aa/120-308 aa) on the N/C terminal, after which the CRT-Cap fusion genes have been expressed in Escherichia coli (E.coli). The dimensions-exclusion chromatography and dynamic gentle scattering (DLS) information confirmed that the purified recombinant CRT-Cap fusion protein (rP5F) existed within the type of polymers.

Immunization with rP5F stimulated excessive ranges of PCV2 particular antibody and neutralization antibody in mice, which have been virtually similar to these induced by the business subunit and inactivated vaccines. The lymphocyte proliferation and cytokine secretion have been additionally detected in rP5F immunized mice. In keeping with the outcomes of PCV2-challenge experiment, the virus masses considerably decreased in mice immunized with rP5F. The info obtained within the present examine revealed that rP5F had the potential to be a subunit vaccine candidate towards PCV2 sooner or later.

Conclusions: We’ve got efficiently expressed Cap-CRT fusion proteins in E.coli and optimized rP5F may kind into immunogenic polymers. Mice immunized with rP5F effectively induced humoral and a part of mobile immune responses and decreased the virus content material towards PCV2-challenge, which advised that rF5P could possibly be a possible subunit vaccine candidate.

An inside amino-terminal FLAG-tag octapeptide alters oligomerization of expressed surfactant protein-A

Pulmonary surfactant protein-A (SP-A) is expressed by lung alveolar and bronchiolar epithelial cells and performs a important function in innate immunity of the lung. Publicity of the lung to numerous environmental insults alters SP-A homeostasis. To research the mobile mechanisms concerned in these alterations, we added the FLAG octapeptide (DYKDDDDK) to the carboxy-terminus (SP-A/C-FLAG) or close to the amino-terminus (SP-A/N-FLAG) of mouse SP-A (WT-SP-A) to tag particular swimming pools of protein. We hypothesized that addition of FLAG would have negligible results on SP-A expression, oligomerization and secretion.

 Evaluation of Chinese language hamster ovary cells expressing these proteins indicated that tagged SP-A mRNA could possibly be distinguished from WT-SP-A by northern evaluation and RT-PCR utilizing sequence-specific oligonucleotides. Tagged SP-A protein could possibly be differentiated from WT-SP-A by western evaluation utilizing antibodies particular for the FLAG epitope.

Subcellular fractionation and immunocytochemistry indicated the vast majority of every protein was current in punctuate (presumably endocytic) vesicles, and all types of SP-A protein have been secreted. These outcomes counsel {that a} FLAG epitope added to the carboxy-terminus or inserted into the amino-terminus of the mature SP-A protein has little impact on its expression and mobile processing.

Nevertheless, disruptions of the amino-terminal finish of SP-A prevents correct oligomerization, suggesting that this area of mature SP-A is important in correct oligomeric meeting and isn’t helpful for research supposed to outline mechanisms underlying SP-A homeostasis.

APC anti-human CD226 (DNAM-1)

E16FHA226-025 25 tests
EUR 455
Description: Available in various conjugation types.

APC anti-human CD226 (DNAM-1)

E16FHA226-100 100 tests
EUR 975
Description: Available in various conjugation types.

FITC anti-human CD226 (DNAM-1)

E16FHF226-025 25 tests
EUR 368.33
Description: Available in various conjugation types.

FITC anti-human CD226 (DNAM-1)

E16FHF226-100 100 tests
EUR 845
Description: Available in various conjugation types.

Purified anti-human CD226 (DNAM-1)

E16FHU226-100U 100 μg
EUR 455
Description: Available in various conjugation types.

Anti-Human CD226/DNAM-1 Antibody (SAA0074)

MBS1564467-01mg 0.1mg
EUR 405

Anti-Human CD226/DNAM-1 Antibody (SAA0074)

MBS1564467-5x01mg 5x0.1mg
EUR 1520

Mouse Monoclonal anti-human DNAM-1 (CD226)

hAP-0248 100ug
EUR 250

Sheep Polyclonal anti-Human DNAM-1 (CD226)

hAP-5851 50ug
EUR 400

Recombinant Human DNAM-1/CD226 Protein

RP00324 10μg
EUR 123.99

Recombinant Human DNAM-1/CD226 Protein

RP00958 10μg
EUR 123.99

Recombinant Human DNAM-1/CD226 Protein

RP02028 100μg
EUR 233.81

Recombinant Human DNAM-1/CD226 Protein

RP02251 10μg
EUR 209.01

PE anti-mouse CD226 (DNAM-1)

E16FMP226-025U 25 μg
EUR 433.33
Description: Available in various conjugation types.

PE anti-mouse CD226 (DNAM-1)

E16FMP226-100U 100 μg
EUR 1148.33
Description: Available in various conjugation types.

DNAM-1 Antibody

B0843-100ul 100μl
EUR 217
Description: DNAM-1 Rabbit Polyclonal Antibody

DNAM-1 Antibody

B0843-50ul 50μl
EUR 143.5
Description: DNAM-1 Rabbit Polyclonal Antibody

DNAM-1 Antibody

C30497-100ul 100μl
EUR 217
Description: DNAM-1 Rabbit Polyclonal Antibody

DNAM-1 Antibody

C30497-50ul 50μl
EUR 143.5
Description: DNAM-1 Rabbit Polyclonal Antibody

APC anti-mouse CD226 (DNAM-1)

E16FMA226-025U 25 μg
EUR 498.33
Description: Available in various conjugation types.

APC anti-mouse CD226 (DNAM-1)

E16FMA226-100U 100 μg
EUR 1256.67
Description: Available in various conjugation types.

FITC anti-mouse CD226 (DNAM-1)

E16FMF226-050U 50 μg
EUR 541.67
Description: Available in various conjugation types.

Human DNAM-1 / CD226 Protein, Fc Tag

DN1-H5257 1mg
EUR 267.5
Description: Human DNAM-1, Fc Tag (DN1-H5257) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - Asn 247 (Accession # NP_006557).

PE Rabbit anti-Human DNAM-1/CD226 mAb

A23591 25μg
EUR 1557.4
Description: Recombinant fusion protein containing a sequence corresponding to amino acids 250-473 of human MEF2A+MEF2C (Q06413).

Human DNAM-1 / CD226 Protein, His Tag

DN1-H52H6 1mg
EUR 267.5
Description: Human DNAM-1, His Tag (DN1-H52H6) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - Asn 247 (Accession # NP_006557).

Human DNAM-1 Protein, mFc-His Tag

E33P100050 10 μg
EUR 225

Human DNAM-1 Protein, mFc-His Tag

MBS8575099-001mg 0.01mg
EUR 305

Human DNAM-1 Protein, mFc-His Tag

MBS8575099-5x001mg 5x0.01mg
EUR 1220

Mouse Monoclonal anti-Human CD226 (DNAM-1) Antibody

xAP-0182 100ug
EUR 280

Mouse Monoclonal anti-Human CD226 (DNAM-1) Antibody

xAP-0183 100ug
EUR 280

Active Recombinant Human DNAM-1/CD226 Protein

RP00283 10 μg
EUR 78

OKRC00369-96W - DNAM-1 ELISA Kit (Human)

OKRC00369-96W 96Wells
EUR 525

Human DNAM-1/CD226 ELISA Kit PicoKine®

EK2161 96 wells/kit, with removable strips.
EUR 499
Description: Human DNAM-1/CD226 ELISA Kit PicoKine® (96 Tests). Quantitate Human CD226 in cell culture supernatants, serum and plasma (heparin, EDTA). Sensitivity: 5 pg/ml.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

AP76445 1mg
EUR 1879

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

CS90-10ug 10ug
EUR 151.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

CS90-1mg 1mg
EUR 1581.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

CS90-500ug 500ug
EUR 1155.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-Fc)

CS90-50ug 50ug
EUR 333.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

NE Purified anti-mouse CD226 (DNAM-1)

E16FMY226-500U 500 μg
EUR 1625
Description: Available in various conjugation types.

Rabbit anti Mouse DNAM-1  Monoclonal Antibody

MBS2544521-006mL 0.06mL
EUR 335

Rabbit anti Mouse DNAM-1  Monoclonal Antibody

MBS2544521-012mL 0.12mL
EUR 520

Rabbit anti Mouse DNAM-1  Monoclonal Antibody

MBS2544521-02mL 0.2mL
EUR 800

CD226 / DNAM-1 Antibody

20-abx119383
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  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

CD226/DNAM-1 Antibody

E11-184778 100ug/100ul
EUR 225
Description: Available in various conjugation types.

CD226/DNAM-1 Antibody

E18-0087-1 50μg/50μl
EUR 145
Description: Available in various conjugation types.

CD226/DNAM-1 Antibody

E18-0087-2 100μg/100μl
EUR 225
Description: Available in various conjugation types.

CD226/DNAM-1 Antibody

AF0087 200ul
EUR 420

CD226/DNAM-1 Antibody

AF4778 200ul
EUR 540

CD226/DNAM-1 Antibody

AF4778-100ul 100ul
EUR 350

CD226/DNAM-1 Antibody

AF4778-200ul 200ul
EUR 450

CD226/DNAM-1 Antibody

AF4778-50ul 50ul
EUR 250

Cd226 Antibody / Dnam-1

RQ6373 100 ug
EUR 356.15
Description: DNAM 1, also known as CD226, is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.

CD226 Antibody / DNAM-1

RQ6841 100ug
EUR 356.15
Description: DNAM 1, also known as CD226, is a receptor expressed by peripheral blood T lymphocytes that is involved in intercellular adhesion, lymphocyte signaling, cytotoxicity and lymphokine secretion mediated by cytotoxic T lymphocytes. DNAM 1 is broadly expressed on T cells, NK cells, platelets, monocytes and a subset of B cells. DNAM-1 is also expressed by a subset of CD3 positive thymocytes. This antibody is reported to inhibit T- and NK cell mediated cytotoxicity against tumour cell targets and to block TNF alpha and IFN gamma secretion by alloantigen-specific T-cells.

CD226/DNAM-1 Antibody

MBS8510593-005mg 0.05mg
EUR 235

CD226/DNAM-1 Antibody

MBS8510593-01mg 0.1mg
EUR 305

CD226/DNAM-1 Antibody

MBS8510593-01mLAF405M 0.1mL(AF405M)
EUR 465

CD226/DNAM-1 Antibody

MBS8510593-01mLAF546 0.1mL(AF546)
EUR 465

CD226/DNAM-1 Antibody

MBS8510593-01mLAF750 0.1mL(AF750)
EUR 465

CD226/DNAM-1 Antibody

MBS8529317-01mg 0.1mg
EUR 305

CD226/DNAM-1 Antibody

MBS8529317-01mLAF405L 0.1mL(AF405L)
EUR 465

CD226/DNAM-1 Antibody

MBS8529317-01mLAF405S 0.1mL(AF405S)
EUR 465

CD226/DNAM-1 Antibody

MBS8529317-01mLAF610 0.1mL(AF610)
EUR 465

CD226/DNAM-1 Antibody

MBS8529317-01mLAF635 0.1mL(AF635)
EUR 465

CD226/DNAM-1 Antibody

MBS9613485-005mL 0.05mL
EUR 245

CD226/DNAM-1 Antibody

MBS9613485-01mL 0.1mL
EUR 305

CD226/DNAM-1 Antibody

MBS9613485-02mL 0.2mL
EUR 365

CD226/DNAM-1 Antibody

MBS9613485-5x02mL 5x0.2mL
EUR 1495

CD226/DNAM-1 Antibody

MBS9503809-005mL 0.05mL
EUR 285

CD226/DNAM-1 Antibody

MBS9503809-01mL 0.1mL
EUR 385

CD226/DNAM-1 Antibody

MBS9503809-5x01mL 5x0.1mL
EUR 1590

CD226/DNAM-1 Antibody

MBS9509278-005mL 0.05mL
EUR 285

CD226/DNAM-1 Antibody

MBS9509278-01mL 0.1mL
EUR 385

CD226/DNAM-1 Antibody

MBS9509278-5x01mL 5x0.1mL
EUR 1590

CD226/DNAM-1 Antibody

MBS9600037-01mL 0.1mL
EUR 260

CD226/DNAM-1 Antibody

MBS9600037-02mL 0.2mL
EUR 305

CD226/DNAM-1 Antibody

MBS9600037-5x02mL 5x0.2mL
EUR 1220

CD226/DNAM-1 Antibody

AF0087-100ul 100ul
EUR 168
Description: WB,IF/ICC,ELISA(peptide)

CD226/DNAM-1 Antibody

AF0087-200ul 200ul
EUR 210
Description: WB,IF/ICC,ELISA(peptide)

Recombinant Human DNAM-1 Protein, Avi & His Tag

E40KMP1218 20ug
EUR 495

Recombinant Human DNAM-1 Protein, Avi & His Tag

E40KMP1892 20ug
EUR 495

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

AP76444 1mg
EUR 1879

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

CS89-10ug 10ug
EUR 151.2
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

CS89-1mg 1mg
EUR 1581.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

CS89-500ug 500ug
EUR 1155.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Recombinant Human CD226 Antigen/DNAM-1/CD226 (C-6His)

CS89-50ug 50ug
EUR 333.6
Description: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Rabbit Polyclonal Anti-CD226/DNAM-1 Antibody

TA347323 100 µg Ask for price

DNAM-1 Polyclonal Antibody

ABP53533-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of DNAM-1 from Human, Mouse, Monkey. This DNAM-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human DNAM-1 around the non-phosphorylation site of S329

DNAM-1 Polyclonal Antibody

ABP53533-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of DNAM-1 from Human, Mouse, Monkey. This DNAM-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human DNAM-1 around the non-phosphorylation site of S329

DNAM-1 Polyclonal Antibody

ABP53533-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of DNAM-1 from Human, Mouse, Monkey. This DNAM-1 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human DNAM-1 around the non-phosphorylation site of S329

DNAM-1 Polyclonal Antibody

ABP53133-003ml 0.03ml
EUR 189.6
Description: A polyclonal antibody for detection of DNAM-1 from Human. This DNAM-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNAM-1

DNAM-1 Polyclonal Antibody

ABP53133-01ml 0.1ml
EUR 346.8
Description: A polyclonal antibody for detection of DNAM-1 from Human. This DNAM-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNAM-1

DNAM-1 Polyclonal Antibody

ABP53133-02ml 0.2ml
EUR 496.8
Description: A polyclonal antibody for detection of DNAM-1 from Human. This DNAM-1 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the Internal region of human DNAM-1

DNAM-1 Polyclonal Antibody

41787-100ul 100ul
EUR 302.4

DNAM-1 Polyclonal Antibody

41787-50ul 50ul
EUR 224.4

DNAM-1 Polyclonal Antibody

40846-100ul 100ul
EUR 302.4

DNAM-1 Polyclonal Antibody

40846-50ul 50ul
EUR 224.4

DNAM-1 Polyclonal Antibody

E040846 100μg/100μl
EUR 255
Description: Available in various conjugation types.

DNAM-1 Polyclonal Antibody

E041787 100μg/100μl
EUR 255
Description: Available in various conjugation types.

DNAM-1 Polyclonal Antibody

E20-75402 100ug
EUR 225
Description: Available in various conjugation types.

DNAM-1 Polyclonal Antibody

E20-71381 100ug
EUR 225
Description: Available in various conjugation types.

DNAM-1 Polyclonal Antibody

E44H06844 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

DNAM-1 Polyclonal Antibody

E44H01772 100ul
EUR 255
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

DNAM-1 Polyclonal Antibody

BT-AP02671-100ul 100ul Ask for price
Description: CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

DNAM-1 Polyclonal Antibody

BT-AP02671-20ul 20ul Ask for price
Description: CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

DNAM-1 Polyclonal Antibody

BT-AP02671-50ul 50ul Ask for price
Description: CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

DNAM-1 Polyclonal Antibody

BT-AP02672-100ul 100ul Ask for price
Description: CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The CD226 molecule mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

DNAM-1 Polyclonal Antibody

BT-AP02672-20ul 20ul Ask for price
Description: CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The CD226 molecule mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

DNAM-1 Polyclonal Antibody

BT-AP02672-50ul 50ul Ask for price
Description: CD226 encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The CD226 molecule mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Alternative splicing results in multiple transcript variants.

DNAM-1 Polyclonal Antibody

MBS9243428-01mL 0.1mL
EUR 415

DNAM-1 Polyclonal Antibody

MBS9243428-5x01mL 5x0.1mL
EUR 1841

DNAM-1 Polyclonal Antibody

MBS9246018-01mL 0.1mL
EUR 415

DNAM-1 Polyclonal Antibody

MBS9246018-5x01mL 5x0.1mL
EUR 1841

DNAM-1 Polyclonal Antibody

MBS9414684-005mL 0.05mL
EUR 245

DNAM-1 Polyclonal Antibody

MBS9414684-01mL 0.1mL
EUR 305

DNAM-1 Polyclonal Antibody

MBS9414684-5x01mL 5x0.1mL
EUR 1230

DNAM-1 Polyclonal Antibody

MBS9405445-005mL 0.05mL
EUR 245

DNAM-1 Polyclonal Antibody

MBS9405445-01mL 0.1mL
EUR 305

DNAM-1 Polyclonal Antibody

MBS9405445-5x01mL 5x0.1mL
EUR 1230

DNAM-1 Polyclonal Antibody

MBS8522362-01mg 0.1mg
EUR 305

DNAM-1 Polyclonal Antibody

MBS8522362-01mLAF405L 0.1mL(AF405L)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8522362-01mLAF405S 0.1mL(AF405S)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8522362-01mLAF610 0.1mL(AF610)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8522362-01mLAF635 0.1mL(AF635)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8526383-01mg 0.1mg
EUR 305

DNAM-1 Polyclonal Antibody

MBS8526383-01mLAF405L 0.1mL(AF405L)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8526383-01mLAF405S 0.1mL(AF405S)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8526383-01mLAF610 0.1mL(AF610)
EUR 465

DNAM-1 Polyclonal Antibody

MBS8526383-01mLAF635 0.1mL(AF635)
EUR 465

DNAM-1 Polyclonal Antibody

MBS2534678-002mL 0.02mL
EUR 140

DNAM-1 Polyclonal Antibody

MBS2534678-006mL 0.06mL
EUR 180

DNAM-1 Polyclonal Antibody

MBS2534678-012mL 0.12mL
EUR 260

DNAM-1 Polyclonal Antibody

MBS2534678-02mL 0.2mL
EUR 405

DNAM-1 Polyclonal Antibody

MBS2534715-002mL 0.02mL
EUR 140

DNAM-1 Polyclonal Antibody

MBS2534715-006mL 0.06mL
EUR 180

DNAM-1 Polyclonal Antibody

MBS2534715-012mL 0.12mL
EUR 260

DNAM-1 Polyclonal Antibody

MBS2534715-02mL 0.2mL
EUR 405

DNAM-1 Polyclonal Antibody

UB-GEN-16420 100 ul
EUR 200

DNAM-1 Polyclonal Antibody

UB-GEN-16494 100 ul
EUR 200

Recombinant Human CD226/DNAM-1 Protein (C-Fc)

MBS2557338-001mg 0.01mg
EUR 155

Recombinant Human CD226/DNAM-1 Protein (C-Fc)

MBS2557338-005mg 0.05mg
EUR 285

Recombinant Human CD226/DNAM-1 Protein (C-Fc)

MBS2557338-5x005mg 5x0.05mg
EUR 1285

Recombinant Human CD226/DNAM-1 Protein (His Tag)

PKSH033728-10ug 10ug
EUR 92
Description: Human

Recombinant Human CD226/DNAM-1 Protein (His Tag)

PKSH033728-50ug 50ug
EUR 268
Description: Human

Recombinant Human CD226 / DNAM-1 Protein (His tag)

MBS2546178-01mg 0.1mg
EUR 685

Recombinant Human CD226 / DNAM-1 Protein (His tag)

MBS2546178-5x01mg 5x0.1mg
EUR 3080

ABflo® 488 Rabbit anti-Human DNAM-1/CD226 mAb

A23175 25μg
EUR 213.2
Description: Recombinant protein of human CD16.

ABflo® 647 Rabbit anti-Human DNAM-1/CD226 mAb

A23176 25μg
EUR 213.2
Description: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human CES1 (P23141).

CD226/DNAM- 1 Antibody

ABF0087 100ug
EUR 325

Recombinant Human CD226 Antigen/DNAM-1/CD226 Protein (C-His)

MBS2557337-001mg 0.01mg
EUR 155

Recombinant Human CD226 Antigen/DNAM-1/CD226 Protein (C-His)

MBS2557337-005mg 0.05mg
EUR 285

Recombinant Human CD226 Antigen/DNAM-1/CD226 Protein (C-His)

MBS2557337-5x005mg 5x0.05mg
EUR 1285

Rat Monoclonal anti-Mouse CD226 (DNAM-1) Antibody

xAP-0583 100ug
EUR 280

Rat Monoclonal anti-Mouse CD226 (DNAM-1) Antibody

xAP-0584 100ug
EUR 280

Biotinylated Human DNAM-1 / CD226 Protein, Fc,Avitag™

DN1-H82F9 25ug
EUR 1722.7
Description: Biotinylated Human DNAM-1, Fc,Avitag (DN1-H82F9) is expressed from human 293 cells (HEK293). It contains AA Glu 19 - Asn 247 (Accession # NP_006557).

Human CD226/DNAM-1 protein, His tag (Animal-Free)

PRP2038-100ug 100 μg
EUR 259
Description: Human CD226/DNAM-1 protein, His tag (Animal-Free), expressed in HEK 293 Cells

Human CD226/DNAM-1 protein, His tag (Animal-Free)

PRP2038-10ug 10 μg
EUR 59
Description: Human CD226/DNAM-1 protein, His tag (Animal-Free), expressed in HEK 293 Cells

Human CD226/DNAM-1 protein, His tag (Animal-Free)

PRP2038-1mg 1 mg
EUR 2369
Description: Human CD226/DNAM-1 protein, His tag (Animal-Free), expressed in HEK 293 Cells

Human CD226/DNAM-1 protein, His tag (Animal-Free)

PRP2038-50ug 50 μg
EUR 139
Description: Human CD226/DNAM-1 protein, His tag (Animal-Free), expressed in HEK 293 Cells

Human CD226/DNAM-1 protein, His tag (Animal-Free)

MBS9719007-001mg 0.01mg
EUR 115

Human CD226/DNAM-1 protein, His tag (Animal-Free)

MBS9719007-005mg 0.05mg
EUR 160

Human CD226/DNAM-1 protein, His tag (Animal-Free)

MBS9719007-01mg 0.1mg
EUR 230

Human CD226/DNAM-1 protein, His tag (Animal-Free)

MBS9719007-1mg 1mg
EUR 1590

Human CD226/DNAM-1 protein, His tag (Animal-Free)

MBS9719007-5x1mg 5x1mg
EUR 7110

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