Characterization of differentially expressed plasma proteins in sufferers with acute

konka-chemica

Prediction of Radioresistant Prostate Most cancers Based mostly on Differentially Expressed Proteins

Introduction: 

Though relapses after radiotherapy are widespread in prostate most cancers (PCA) sufferers, these with a excessive threat for radioresistance can’t be recognized previous to therapy but. Subsequently, this proof-of-concept research was carried out to check protein expression profiles of sufferers with radio-recurrent PCA to sufferers handled with major radical prostatectomy separated by Gleason threat teams. We hypothesized that radio-recurrent PCA have an analogous protein expression as high-risk Gleason PCA.

Strategies:

Affected person cohorts consisted of (i) 31 sufferers handled with salvage prostatectomy for regionally recurrent PCA after major radiotherapy and (ii) 94 sufferers handled with major prostatectomy break up right into a Gleason high-risk (≥4 + 3; n = 42 [44.7%]) versus a low-risk group (≤3 + 4; n = 52 [55.3%]). Immunohistochemistry was carried out utilizing 15 antibodies with identified affiliation to radioresistance in PCA in vitro. ELISA was used for validation of chosen markers in serum.

Outcomes: 

Androgen receptor (AR) was overexpressed in most radio-recurrent PCA (89.7%) and in most major high-risk Gleason PCA (87.8%; p = 0.851), whereas solely 67.3% of the low-risk group confirmed an expression (p = 0.017). Contemplating the best Gleason sample in major PCA, aldo-keto reductase household 1 member C3 (AKR1C3) was most equally expressed by sufferers with radio-recurrent PCA and sufferers with Gleason patterns Four and 5 (p = 0.827 and p = 0.893) in comparison with Gleason sample 3 (p = 0.20). These findings had been supported by ELISA.

Conclusion:

That is the primary research to judge protein markers with a purpose to predict radioresistance in PCA. Our outcomes level to AR and AKR1C3 as essentially the most promising markers which may assist stratify sufferers for radiotherapy.

konka-chemica
konka-chemica

AXYGEN® GEL TRAY 15 X 15 CM FOR USE WITH 15 CM GEL BOX, UV TRANSPARENT

HGB15-15-GT 1/pk
EUR 79
Description: Lab Equipment; Axygen Branded EQ

DiagNano Gold Nanoparticle Passive Conjugation Kit, 15 nm

GPK-15 1 kit
EUR 715

Anti-Human IgG

DB173RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Human IgG

DB174RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Sheep CCL-5 ELISA Kit

ESC0240 96Tests
EUR 521

Mouse CCL-5 ELISA Kit

EMC0240 96Tests
EUR 521

Anserini CCL-5 ELISA Kit

EAC0240 96Tests
EUR 521

Rabbit CCL-5 ELISA Kit

ERTC0240 96Tests
EUR 521

Monkey CCL-5 ELISA Kit

EMKC0240 96Tests
EUR 521

Porcine CCL-5 ELISA Kit

EPC0240 96Tests
EUR 521

Rat CCL-5 ELISA Kit

ERC0240 96Tests
EUR 521

Canine CCL-5 ELISA Kit

ECC0240 96Tests
EUR 521

Chicken CCL-5 ELISA Kit

ECKC0240 96Tests
EUR 521

Goat CCL-5 ELISA Kit

EGTC0240 96Tests
EUR 521

Bovine CCL-5 ELISA Kit

EBC0240 96Tests
EUR 521

Anti-Human Kappa Light Chain

DB037RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Human Kappa Light Chain

DB038RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Human Lambda Light Chain

DB039RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 280

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

Guinea Pig CCL-5 ELISA Kit

EGC0240 96Tests
EUR 521

Anti-iNOS

DB003RTU-15 15 ml
EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-p53

DB026RTU-15 15 ml
EUR 338
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD5

DB027RTU-15 15 ml
EUR 414
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD20

DB041RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD45

DB042RTU-15 15 ml
EUR 338
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163

DB045RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Melanosome

DB049RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD10

DB057RTU-15 15 ml
EUR 414
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD117

DB062RTU-15 15 ml
EUR 338
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD1a

DB071RTU-15 15 ml
EUR 414
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD3

DB082RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD8

DB085RTU-15 15 ml
EUR 414
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-EGFR

DB092RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD7

DB114RTU-15 15 ml
EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-MSH2

DB115RTU-15 15 ml
EUR 400
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-p63

DB134RTU-15 15 ml
EUR 347
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD23

DB135RTU-15 15 ml
EUR 429
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Desmin

DB148RTU-15 15 ml
EUR 347
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD34

DB151RTU-15 15 ml
EUR 347
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-p16

DB152RTU-15 15 ml
EUR 347
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Synaptophysin

DB156RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Braf

DB159RTU-15 15 ml
EUR 709
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-p60

DB203RTU-15 15 ml
EUR 347
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

DiagNano Fluorophore Labeled Gold Nanoparticles, 15 nm, Cellular Uptake

GFL-15-CU 1mL
EUR 1365

DiagNano Gold Nanoparticle Medium Covalent Conjugation Kit, 15 nm

GCK-M-15 1 kit
EUR 757

Anti-b-actin

DB001RTU-15 15 ml
EUR 265
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Melan A

DB050RTU-15 15 ml
EUR 302
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 7

DB051RTU-15 15 ml
EUR 309
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-S-100

DB055RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cyclin D1

DB066RTU-15 15 ml
EUR 414
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Ki-67

DB070RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-TTF-1

DB089RTU-15 15 ml
EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 8

DB098RTU-15 15 ml
EUR 309
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 14

DB099RTU-15 15 ml
EUR 302
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 16

DB100RTU-15 15 ml
EUR 302
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 17

DB101RTU-15 15 ml
EUR 302
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 18

DB102RTU-15 15 ml
EUR 265
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 19

DB103RTU-15 15 ml
EUR 265
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-C3d complement

DB106RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-C4d complement

DB107RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Ki-67

DB111RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 20

DB119RTU-15 15 ml
EUR 309
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Chromogranin A

DB158RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-P504S (AMACR)

DB208RTU-15 15 ml
EUR 340
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

anti-Cytokeratin 15

YF-PA12886 100 ul
EUR 403
Description: Rabbit polyclonal to Cytokeratin 15

anti-Cytokeratin 15

YF-PA12887 100 ug
EUR 403
Description: Rabbit polyclonal to Cytokeratin 15

anti-Claudin 15

YF-PA18066 50 ug
EUR 363
Description: Mouse polyclonal to Claudin 15

anti-Claudin 15

YF-PA18067 100 ug
EUR 403
Description: Rabbit polyclonal to Claudin 15

anti-Kallikrein 15

YF-PA19752 50 ul
EUR 363
Description: Mouse polyclonal to Kallikrein 15

anti-Calpain 15

YF-PA24745 50 ul
EUR 334
Description: Mouse polyclonal to Calpain 15

Anti-Human GCDFP-15 antibody

STJ16100371 1 mL
EUR 956

Anti-ER (Estrogen Receptor)

DB053RTU-15 15 ml
EUR 406
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-PR (Progesterone Receptor)

DB059RTU-15 15 ml
EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-EBV/LMP-1

DB060RTU-15 15 ml
EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-EBV/LMP-1

DB061RTU-15 15 ml
EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 5/6

DB097RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-PR (Progesterone Receptor)

DB108RTU-15 15 ml
EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-PR (Progesterone Receptor)

DB109RTU-15 15 ml
EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-p16 (mouse monoclonal)

DB253RTU-15 15 ml
EUR 347
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

TruStrip Sample Transfer Strips, 15-ul, 50/Pk (without sample tracking dye)

STS-15-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 15-ul, 50/Pk (with sample tracking dye)

STSD-15-50 1 Pk Ask for price

Anti-PLAP (Placental Alkaline Phosphatase)

DB047RTU-15 15 ml
EUR 265
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-EMA (CD227, Mucin-1)

DB048RTU-15 15 ml
EUR 265
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Alpha Smooth Muscle Actin

DB147RTU-15 15 ml
EUR 347
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Human IgG

DB-173-RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Human IgG

DB-174-RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-C-erbB-2 (Her-2/neu)

DB094RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Goat IgG Secondary antibody Clone: pAb to UltraPolymer Goat Anti-Human IgG (H&L) HRP

A1278-15 15 ml
EUR 322
Description: Goat IgG Secondary antibody Clone: pAb against UltraPolymer Goat Anti-Human IgG (H&L) HRPfor application in IHC.The immunogen is Human IgG (H&L).This antibody can be used for detection of the target molecule in samples from Human.

Anti-GDF-15 Antibody

A2038-100 100 µl
EUR 419

Anti-Calpain 15 (4E2)

YF-MA15522 100 ug
EUR 363
Description: Mouse monoclonal to Calpain 15

Anti-Calpain 15 (2H7)

YF-MA15523 100 ug
EUR 363
Description: Mouse monoclonal to Calpain 15

anti-15 Lipoxygenase 1

YF-PA10168 100 ug
EUR 403
Description: Rabbit polyclonal to 15 Lipoxygenase 1

anti-Protease Inhibitor 15

YF-PA18816 50 ul
EUR 363
Description: Mouse polyclonal to Protease Inhibitor 15

anti-CDC2 (Ab-15)

LF-PA20070 100 ul
EUR 334
Description: Rabbit polyclonal to CDC2

anti-HSP27 (Ab-15)

LF-PA20219 100 ul
EUR 334
Description: Rabbit polyclonal to HSP27

anti-p53 (Ab-15)

LF-PA20358 100 ul
EUR 334
Description: Rabbit polyclonal to p53

Anti-Cytokeratin 15 antibody

PAab02198 100 ug
EUR 355

Anti-MMP-15 Antibody

A06396 100ul
EUR 397
Description: Rabbit Polyclonal MMP-15 Antibody. Validated in WB and tested in Human, Mouse.

Anti-Cytokeratin 15 Antibody

A06791 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Cytokeratin 15 Antibody (KRT15) detection.tested for WB in Human, Mouse, Rat, Monkey.

Anti-DHHC-15 Antibody

A12099 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for DHHC-15 Antibody (ZDHHC15) detection. Tested with WB in Human.

Anti-GCDFP-15 antibody

STJ16100370 1 mL
EUR 813

Anti-GCDFP-15 antibody

STJ180109 0.1 ml
EUR 213

Anti-GCDFP-15 antibody

STJ180290 0.1 ml
EUR 212

Anti-CK-15 antibody

STJ190030 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to CK-15 (5A1)

Anti-BMP-15 antibody

STJ97345 200 µl
EUR 197
Description: Rabbit polyclonal to BMP-15.

Anti-Cytokeratin 15 antibody

STJ97982 100 µl
EUR 234
Description: Mouse monoclonal to Cytokeratin 15.

Anti-Cytokeratin 15 antibody

STJ92628 200 µl
EUR 197
Description: Rabbit polyclonal to Cytokeratin 15.

Anti-DHHC-15 antibody

STJ92707 200 µl
EUR 197
Description: Rabbit polyclonal to DHHC-15.

Anti-GDF-15 antibody

STJ93253 200 µl
EUR 197
Description: Rabbit polyclonal to GDF-15.

Anti-MMP-15 antibody

STJ94276 200 µl
EUR 197
Description: Rabbit polyclonal to MMP-15.

Anti-PEA-15 antibody

STJ95018 200 µl
EUR 197
Description: Rabbit polyclonal to PEA-15.

Anti-PEA-15 antibody

STJ95019 200 µl
EUR 197
Description: Rabbit polyclonal to PEA-15.

Anti-PEA-15 antibody

STJ95020 200 µl
EUR 197
Description: Rabbit polyclonal to PEA-15.

Anti-IL-15 antibody

STJ99006 200 µl
EUR 197
Description: Rabbit polyclonal to IL-15.

anti- Cytokeratin 15 antibody

FNab02198 100µg
EUR 505.25
Description: Antibody raised against Cytokeratin 15

anti- Cytokeratin 15 antibody

FNab02199 100µg
EUR 548.75
Description: Antibody raised against Cytokeratin 15

IL-15, Interleukin-15, human

RC212-26 2ug
EUR 104.38

UltraPolymer Goat Anti-Rabbit IgG (H&L) HRP

A1274-15
EUR 321

UltraPolymer Goat Anti-Mouse IgG (H&L) HRP

A1275-15
EUR 321

UltraPolymer Donkey Anti-Goat IgG (H&L) HRP

A1276-15
EUR 321

UltraPolymer Goat Anti-Rat IgG (H&L) HRP

A1277-15
EUR 338

UltraPolymer Donkey Anti-Sheep IgG (H&L) HRP

A1279-15
EUR 321

AXYGEN® 10-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-10-15 1/pk
EUR 60
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 12-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-12-15 1/pk
EUR 60
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 20-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-20-15 1/pk
EUR 60
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 35-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-35-15 1/pk
EUR 69
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-8-15 1/pk
EUR 69
Description: Lab Equipment; Axygen Branded EQ

T3 (Triiodothyronine) ELISA test

15 96T/Box Ask for price
Description: ELISA based test for quantitative detection of T3 (Triiodothyronine)

Anti-CD15

DB211-RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD21

DB213-RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD57

DB216-RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

UltraPolymer Goat Anti-Rabbit/Mouse IgG (H&L) HRP Cocktail

A1280-15
EUR 321

Anti-Dimethyl Histone H3 (Lys14) Rabbit Monoclonal Antibody, Clone#RM165

M06819-15 100ug
EUR 468
Description: Anti-Dimethyl Histone H3 (Lys14) Rabbit Monoclonal Antibody, Clone#RM165 tested in WB, ELISA, Multiplex, reactive to All Vertebrates

Recombinant Human Interleukin-15/IL-15

C016-10ug 10ug
EUR 202
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.

Recombinant Human Interleukin-15/IL-15

C016-1mg 1mg
EUR 1836
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.

Recombinant Human Interleukin-15/IL-15

C016-500ug 500ug
EUR 1298
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.

Recombinant Human Interleukin-15/IL-15

C016-50ug 50ug
EUR 496
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.

Human Interleukin-15 (IL-15) Antibody

30145-05111 150 ug
EUR 261

AXYGEN® 14-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-14MC-15 1/pk
EUR 63
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 16-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-16MC-15 1/pk
EUR 60
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 18-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-18MC-15 1/pk
EUR 60
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 28-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-28MC-15 1/pk
EUR 62
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 30-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-30MC-15 1/pk
EUR 62
Description: Lab Equipment; Axygen Branded EQ

Anti-PD-L1

DB241-RTU-15 15 ml
EUR 678
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Human Kappa Light Chain

DB-037-RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Human Kappa Light Chain

DB-038-RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Human Lambda Light Chain

DB-039-RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Rabbit Anti Human Interleukin-15 Polyclonal Antibody

CPBT-65643RH 0.1 mg
EUR 881

Mouse Monoclonal Anti-Human Interleukin-15 IgG

AB-11510 100 ug
EUR 347

EPO, human

RC213-15 500U
EUR 104.38

Anti-15 Lipoxygenase 1 (3D8)

YF-MA10038 100 ug
EUR 363
Description: Mouse monoclonal to 15 Lipoxygenase 1

Anti-Protease Inhibitor 15 (3B5)

YF-MA11488 100 ug
EUR 363
Description: Mouse monoclonal to Protease Inhibitor 15

Anti-15 Lipoxygenase 1 (1A11)

YF-MA11900 100 ug
EUR 363
Description: Mouse monoclonal to 15 Lipoxygenase 1

Anti-15 Lipoxygenase 2 (4A7)

YF-MA11901 100 ug
EUR 363
Description: Mouse monoclonal to 15 Lipoxygenase 2

anti-Stathmin 1 (Ab-15)

LF-PA20485 100 ul
EUR 334
Description: Rabbit polyclonal to Stathmin 1

Anti-15 Lipoxygenase 2 antibody

PAab00005 100 ug
EUR 355

Anti-GCDFP-15/PIP antibody

PAab03381 100 ug
EUR 412

Anti-CDC2 (Ab-15) Antibody

A00209 100ul
EUR 397
Description: Rabbit Polyclonal CDC2 (Ab-15) Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-Cytokeratin 15 Monoclonal Antibody

A06791-1 100ul
EUR 397
Description: Mouse Monoclonal Antibody for Cytokeratin 15 Antibody (KRT15) detection.tested for Flow Cytometry, IF, IHC, WB in Human.

Anti-IL-15 alpha antibody

STJ93680 200 µl
EUR 197
Description: Rabbit polyclonal to IL-15Ralpha.

anti- GCDFP-15/PIP antibody

FNab03381 100µg
EUR 585
Description: Antibody raised against GCDFP-15/PIP

anti- 15 Lipoxygenase 2 antibody

FNab00005 100µg
EUR 505.25
Description: Antibody raised against 15 Lipoxygenase 2

LIGHT, Human Recombinant

P1291-15
EUR 370

FGF-4, human

RC215-15 5ug
EUR 104.38

1-step Polymer HISTO-STAT; HRP anti Mouse for staining Mouse and Rat antibodies, 250 plus slides

NB312M-15 15 ml
EUR 427

1-step Polymer HISTO-STAT; HRP anti Rat (SecondaryReagent Component) for staining Rat antibodies, 250 plus slides

NB312T-15 15 ml
EUR 427

IL-15, Human

HY-P7034 50ug
EUR 670

Human Interleukin 15,IL-15 ELISA KIT

CN-03216H1 96T
EUR 434

Human Interleukin 15,IL-15 ELISA KIT

CN-03216H2 48T
EUR 284

Human Interleukin-15 (IL-15) ELISA Kit

LF-EK60041 1×96T
EUR 790

Human Interleukin 15, IL-15 ELISA KIT

CSB-E04603h-24T 1 plate of 24 wells
EUR 165
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 15, IL-15 in samples from serum, plasma, tissue homogenates, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Interleukin 15, IL-15 ELISA KIT

1-CSB-E04603h
  • EUR 603.00
  • EUR 4247.00
  • EUR 2260.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 15, IL-15 in samples from serum, plasma, tissue homogenates, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Interleukin 15,IL-15 ELISA KIT

201-12-0098 96 tests
EUR 440
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Interleukin 15 (IL-15) CLIA Kit

abx195854-96tests 96 tests
EUR 825

IL-15 Interleukin-15 Human Recombinant Protein

PROTP40933 Regular: 10ug
EUR 317
Description: Interleukin-15 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 114 amino acids (and an N-terminal Methionine) and having a molecular mass of 12.8kDa. The IL-15 is purified by proprietary chromatographic techniques.

Human Interleukin 15(IL-15)ELISA Kit

GA-E0137HM-48T 48T
EUR 289

Human Interleukin 15(IL-15)ELISA Kit

GA-E0137HM-96T 96T
EUR 466

Human IL-15(Interleukin 15) ELISA Kit

EH0177 96T
EUR 476.25
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml

Human Interleukin 15(IL-15)ELISA Kit

QY-E04325 96T
EUR 361

1-step Polymer HISTO-STAT; HRP anti Chicken (Secondary Reagent Component) for staining Chicken antibodies, 250 plus slides

NB312C-15 15 ml
EUR 485

1-step Polymer HISTO-STAT; HRP anti Goat (Secondary Reagent Component) for staining Goat antibodies, 250 plus slides

NB312G-15 15 ml
EUR 485

1-step Polymer HISTO-STAT; HRP anti Hamster (Secondary Reagent Component) for staining Hamster antibodies, 250 plus slides

NB312H-15 15 ml
EUR 485

The ribotoxin-like protein Ostreatin from Pleurotus ostreatus fruiting our bodies: Affirmation of a novel ribonuclease household expressed in basidiomycetes

Fungi produce a number of toxins energetic towards crops, animal or people. Amongst them, ribotoxins are enzymes that particularly assault ribosomes irreparably compromising protein synthesis, helpful as pesticides or as anticancer brokers. Right here, a novel ribotoxin from the edible mushroom Pleurotus ostreatus has been purified and characterised.

This ribotoxin, named Ostreatin, is a particular ribonuclease releasing α-fragment when incubated with yeast or rabbit ribosomes. Ostreatin exhibits IC50 of 234 pM in rabbit reticulocyte lysate, and metallic dependent endonuclease exercise. Following the completion of Ostreatin major construction, we ascertained that this toxin is homologous to Ageritin, the primary ribotoxin-like protein from the basidiomycete Agrocybe aegerita, with which it shares 38.8% amino acid sequence identification.

 Ostreatin consists of 131 amino acid residues with an experimental molecular mass of 14,263.51 Da ([M+H+]+). Homology modeling revealed that Ostreatin and Ageritin share an analogous fold by which the widespread catalytic triad is conserved.

Purified Ostreatin lacks N-terminal and C-terminal peptides, which as an alternative are current within the Ostreatin coding sequence. Such peptides are in all probability concerned in protein sorting and for this they might be eliminated. Our findings affirm the presence of ribotoxin-like proteins in basidiomycetes edible mushrooms, that we suggest as novel instrument for biotechnological functions.

Characterization of differentially expressed plasma  proteins in sufferers with acute myocardial infarction

Acute myocardial infarction (AMI) stays a number one reason for morbidity and mortality worldwide. Novel biomarkers are wanted to establish NSTEMI in AMI sufferers. The research goal was to make use of proteomics to establish novel plasma biomarkers for STEMI and NSTEMI sufferers. iTRAQ evaluation was carried out on pooled samples from Eight wholesome controls and 12 STEMI and 12 NSTEMI sufferers.

 Bioinformatics evaluation recognized 95 differentially expressed proteins that had been differentially expressed within the plasma of AMI sufferers and wholesome controls; 28 of those proteins had been present in STEMI/Con (22 upregulated and 6 downregulated), 48 in NSTEMI/Con (12 upregulated and 36 downregulated), and 44 in NSTEMI/STEMI (11 upregulated and 33 downregulated). Protein community evaluation was then carried out utilizing STRING software program.

Practical evaluation revealed that the recognized plasma proteins had been primarily concerned with carbon metabolism, toll-like receptor signaling pathway, and hypertrophic cardiomyopathy. 9 of the proteins (SSA1, MDH1, FCN2, GPI, S100A8, LBP, vinculin, VDBP, and RBP4) that modified ranges throughout AMI development had been additional validated by ELISA. The constructed plasma proteome may mirror the AMI pathogenesis molecular mechanisms and supply a technique for the early identification of NSTEMI in AMI sufferers. SIGNIFICANCE:

The goal of this research was to make use of proteomics to establish novel predictive plasma biomarkers for sufferers with acute myocardial infarction (AMI), which might enable for both identification of people liable to an infarction, and early identification of NSTEMI in sufferers with AMI. Utilizing an strategy that mixed iTRAQ with LC-MS/MS, we discovered 95 proteins that confirmed vital variations in expression ranges among the many AMI sufferers and wholesome controls.

The proteins SSA1, MDH1, FCN2, GPI, S100A8, LBP, vinculin, VDBP, and RBP4 had been discovered to play essential roles within the pathogenesis of AMI. Utilizing bioinformatics evaluation, we discovered that dysregulation of carbon metabolism, toll-like receptor signaling pathway, and hypertrophic cardiomyopathy would be the main driving forces for cardiac harm throughout myocardial infarction.

Nonetheless, additional investigations are wanted to confirm the mechanisms concerned within the improvement of AMI particularly NSTEMI. Taken collectively, our findings lay the muse for understanding the molecular mechanisms underlying the pathogenic processes of AMI, and recommend potential functions for particular biomarkers in early prognosis and willpower of prognosis.

Accuris Taq Master Mix

PR1001-200 1 PC
EUR 121.62

Accuris Taq Master Mix

PR1001-S 1 PC
EUR 69.79

2 × Taq Plus Master Mix

P211-01 5 ml
EUR 134

2 × Taq Plus Master Mix

P211-02 15 ml
EUR 193

2 × Taq Plus Master Mix

P211-03 50 ml
EUR 389

2 × Rapid Taq Master Mix

P222-01 5 ml (5×1ml)
EUR 120

2 × Rapid Taq Master Mix

P222-02 15 ml (15×1ml)
EUR 153

2 × Rapid Taq Master Mix

P222-03 50 ml (50 x 1 ml)
EUR 257

2 × Rapid Taq Master Mix

P222-04 50 ml (10×5ml)
EUR 257

Accuris Taq Plus Master Mix

PR1001-TP-1000 1 PC
EUR 827.41

Accuris Taq Plus Master Mix

PR1001-TP-200 1 PC
EUR 242.84

Accuris Taq Plus Master Mix

PR1001-TP-S 1 PC
EUR 69.79

2× EpiArt HS Taq Master Mix

EM201-01 1ml
EUR 145

2× EpiArt HS Taq Master Mix

EM201-02 5 ml (5×1ml)
EUR 303

2× EpiArt HS Taq Master Mix

EM201-03 15 ml (15×1ml)
EUR 642

2 × Taq Master Mix (Dye Plus)

P112-01 5 ml
EUR 117

2 × Taq Master Mix (Dye Plus)

P112-02 15 ml
EUR 146

2 × Taq Master Mix (Dye Plus)

P112-03 50 ml
EUR 236

Accuris Hot Start Taq Master Mix

PR1001-HS-1000 1 PC
EUR 490.87

Accuris Hot Start Taq Master Mix

PR1001-HS-200 1 PC
EUR 169.47

Accuris Taq Master Mix Red Dye

PR1001-R-1000 1 PC
EUR 300.26

Accuris Taq Master Mix Red Dye

PR1001-R-200 1 PC
EUR 121.62

Accuris Taq Master Mix Red Dye

PR1001-R-S 1 PC
EUR 69.79

2 × Taq Plus Master Mix (Dye Plus)

P212-01 5 ml
EUR 133

2 × Taq Plus Master Mix (Dye Plus)

P212-02 15 ml
EUR 193

2 × Taq Plus Master Mix (Dye Plus)

P212-03 50 ml
EUR 389

Taq PCR Master Mix (2X, Blue Dye)

BS9295 1ml
EUR 84.8

Taq PCR Master Mix (2X, Blue Dye)

BS9296 5ml
EUR 189.2

Taq PCR Master Mix (2X, Red Dye)

BS9297 1ml
EUR 84.8

Taq PCR Master Mix (2X, Red Dye)

BS9298 5ml
EUR 189.2

2×Taq PCR Master Mix(with dye)

K1034-1 1 ml
EUR 73

2×Taq PCR Master Mix(with dye)

K1034-100 100×1 ml
EUR 792

2×Taq PCR Master Mix(with dye)

K1034-20 20×1 ml
EUR 282

2×Taq PCR Master Mix(with dye)

K1034-5 5×1 ml
EUR 119

2×Taq PCR Master Mix(with dye)

K1034-50 50×1 ml
EUR 514

2× EpiArt HS Taq Master Mix (Dye Plus)

EM202-01 1ml
EUR 145

2× EpiArt HS Taq Master Mix (Dye Plus)

EM202-02 5 ml (5×1ml)
EUR 303

2× EpiArt HS Taq Master Mix (Dye Plus)

EM202-03 15 ml (15×1ml)
EUR 642

2 × Taq Plus Master Mix II (Dye Plus)

P213-01 5 ml
EUR 134

2 × Taq Plus Master Mix II (Dye Plus)

P213-02 15 ml
EUR 193

2 × Taq Plus Master Mix II (Dye Plus)

P213-03 50 ml
EUR 389

Accuris Hot Start Taq Master Mix Red Dye

PR1001-HSR-1000 1 PC
EUR 490.87

Accuris Hot Start Taq Master Mix Red Dye

PR1001-HSR-200 1 PC
EUR 169.47

Accuris Hot Start Taq Master Mix Red Dye

PR1001-HSR-S 1 PC
EUR 69.79

Hot Start Taq 2x Master Mix - 500 Reactions

3296 1/EA
EUR 268

Green Taq Mix

P131-01 5 ml
EUR 119

Green Taq Mix

P131-02 15 ml
EUR 150

Green Taq Mix

P131-03 50 ml
EUR 248

Jade? Master Mix

M1105-500
EUR 441

Taqman Master Mix

M1121-500
EUR 441

2 × AceTaq Master Mix

P411-01 1 ml
EUR 119

2 × AceTaq Master Mix

P411-02 5 ml
EUR 158

2 × AceTaq Master Mix

P411-03 15 ml
EUR 262

Taqman Master Mix-iCycler

M1122-500
EUR 441

Taqman Master Mix-ROX

M1124-500
EUR 441

Taqman Master Mix-Multiplex

M1125-500
EUR 441

amfiSure PCR Master Mix

P0311-010 2x50 rxns
EUR 126

amfiSure PCR Master Mix

P0311-025 5X50 rxns
EUR 165

amfiSure PCR Master Mix

P0311-050 10X50 rxns
EUR 219

amfiSure PCR Master Mix

P0311-100 10x1ml
EUR 286

amfiSure PCR Master Mix

P0311-125 15X50 rxns
EUR 278

amfiSure PCR Master Mix

P0311-200 20x1ml
EUR 469

amfiSure PCR Master Mix

P0311-250 50x50 rxns
EUR 752

amfiSure PCR Master Mix

P0311-500 100x50 rxns
EUR 1258

amfiXpand PCR Master Mix

P0331-010 2X50 rxns
EUR 151

amfiXpand PCR Master Mix

P0331-025 5X50 rxns
EUR 273

amfiXpand PCR Master Mix

P0331-050 10X50 rxns
EUR 448

amfiXpand PCR Master Mix

P0331-250 50x50 rxns
EUR 1873

2 × Phanta Max Master Mix

P515-01 1 ml
EUR 145

2 × Phanta Max Master Mix

P515-02 5 ml
EUR 269

2 × Phanta Max Master Mix

P515-03 15 ml
EUR 575

2 × Vazyme LAmp Master Mix

P311-01 1 ml
EUR 137

2 × Vazyme LAmp Master Mix

P311-02 5 ml
EUR 212

2 × Vazyme LAmp Master Mix

P311-03 15 ml
EUR 401

Taqman Master Mix-Low ROX

M1123-500
EUR 441

AceQ qPCR Probe Master Mix

Q112-02 500 rxn (20 μl/rxn)
EUR 221

AceQ qPCR Probe Master Mix

Q112-03 2500 rxn (20 μl/rxn)
EUR 646

AceQ U+ Probe Master Mix

Q113-02 500 rxn (20 μl/rxn)
EUR 267

AceQ U+ Probe Master Mix

Q113-03 2500 rxn (20 μl/rxn)
EUR 842

Seamless cloning Master Mix (Kit)

B632219 40RXN, 40prep
EUR 266.63

SYBR Green qPCR Master Mix

HY-K0501 5 mL (500 rxns)
EUR 263

RT Master Mix for qPCR

HY-K0510 1 mL (100 rxns)
EUR 291

amfiSure Prime PCR Master Mix

P1311-025 5X50 rxns
EUR 161

amfiSure Prime PCR Master Mix

P1311-050 10X50 rxns
EUR 219

amfiSure Prime PCR Master Mix

P1311-125 15X50 rxns
EUR 273

amfiSure Prime PCR Master Mix

P1311-250 50x50 rxns
EUR 739

amfiSure Prime PCR Master Mix

P1311-500 100x50 rxns
EUR 1238

amfiSure Advanced PCR Master Mix

P2311-025 5X50 rxns
EUR 165

amfiSure Advanced PCR Master Mix

P2311-050 10X50 rxns
EUR 223

amfiSure Advanced PCR Master Mix

P2311-125 15X50 rxns
EUR 282

amfiSure Advanced PCR Master Mix

P2311-250 50x50 rxns
EUR 752

amfiSure Advanced PCR Master Mix

P2311-500 100x50 rxns
EUR 1279

amfiRivert cDNA Synthesis Master Mix

R5101-050 50 rxns
EUR 415

amfiRivert cDNA Synthesis Master Mix

R5101-100 2X50 rxns
EUR 847

amfiRivert cDNA Synthesis Master Mix

R5101-200 4X50 rxns
EUR 1211

Taq 2x PCR Mix 100 rxn

BA01501 100rxn
EUR 94
Description: High quality Taq polymerase for different PCR variations and downstream applications.

Taq 5x PCR Mix 12.5 mM

BT10402 250rxn
EUR 109
Description: High quality Taq polymerase for different PCR variations and downstream applications.

2x SYBR Green qPCR Master Mix

B21202 5 mL
EUR 224
Description: Our 2x SYBR Green qPCR master mix performs toe to toe in all qPCR assays with the most well known brands on the market but surpases them significantly in cost-efficiency.

2x SYBR Green qPCR Master Mix

B21203 25 mL
EUR 856
Description: Our 2x SYBR Green qPCR master mix performs toe to toe in all qPCR assays with the most well known brands on the market but surpases them significantly in cost-efficiency.

2 × AceTaq Master Mix (Dye Plus)

P412-01 1 ml
EUR 119

2 × AceTaq Master Mix (Dye Plus)

P412-02 5 ml
EUR 158

2 × AceTaq Master Mix (Dye Plus)

P412-03 15 ml
EUR 262

AceQ Universal SYBR qPCR Master Mix

Q511-02 500 rxn (20 μl/rxn)
EUR 221

AceQ Universal SYBR qPCR Master Mix

Q511-03 2500 rxn (20 μl/rxn)
EUR 646

ChamQ Universal SYBR qPCR Master Mix

Q711-02 500 rxn (20 μl/rxn)
EUR 221

ChamQ Universal SYBR qPCR Master Mix

Q711-03 2500 rxn (20 μl/rxn)
EUR 646

ChamQ Geno-SNP Probe Master Mix

Q811-02 500 rxn (20 μl/rxn)
EUR 277

ChamQ Geno-SNP Probe Master Mix

Q811-03 2500 rxn (20 μl/rxn)
EUR 923

PCR-EZ D-PCR MASTER MIX

BS294 100RXN, 100prep
EUR 93.5

Pfu 2x Master Mix - 200 Reactions

3326 1/EA
EUR 300

Maximo Dry-Master Mix (Lyophilized Polymerase)

S295 192 rcs (20µl, in plates or tubes)
EUR 133

Fast Probe Master Mix (200 rxn)

31005 2x1ML
EUR 234
Description: Minimum order quantity: 1 unit of 2x1ML

Fast Probe Master Mix (500 rxn)

31005-1 5x1ML
EUR 466
Description: Minimum order quantity: 1 unit of 5x1ML

Fast Probe Master Mix (5000 rxn)

31005-2 50x1ML
EUR 3871
Description: Minimum order quantity: 1 unit of 50x1ML

amfiSure ONE PCR Master Mix(2X)

P7000-005 5x1 ml
EUR 219

amfiSure ONE PCR Master Mix(2X)

P7000-010 10x1 ml
EUR 317

amfiSure ONE PCR Master Mix(2X)

P7000-050 50x1 ml
EUR 1211

amfiSure ONE PCR Master Mix(2X)

P7000-100 100x1 ml
EUR 2102

amfiRivert II cDNA Synthesis Master Mix

R5500-050 50 rxns
EUR 374

amfiRivert II cDNA Synthesis Master Mix

R5500-100 2x50rxns
EUR 577

amfiRivert cDNA Synthesis Prime Master Mix

R5610-050 50 rxns
EUR 412

amfiRivert cDNA Synthesis Prime Master Mix

R5610-100 2x50 rxns
EUR 671

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