Characterization of differentially expressed plasma proteins in sufferers with acute

konka-chemica

Prediction of Radioresistant Prostate Most cancers Based mostly on Differentially Expressed Proteins

Introduction: 

Though relapses after radiotherapy are widespread in prostate most cancers (PCA) sufferers, these with a excessive threat for radioresistance can’t be recognized previous to therapy but. Subsequently, this proof-of-concept research was carried out to check protein expression profiles of sufferers with radio-recurrent PCA to sufferers handled with major radical prostatectomy separated by Gleason threat teams. We hypothesized that radio-recurrent PCA have an analogous protein expression as high-risk Gleason PCA.

Strategies:

Affected person cohorts consisted of (i) 31 sufferers handled with salvage prostatectomy for regionally recurrent PCA after major radiotherapy and (ii) 94 sufferers handled with major prostatectomy break up right into a Gleason high-risk (≥4 + 3; n = 42 [44.7%]) versus a low-risk group (≤3 + 4; n = 52 [55.3%]). Immunohistochemistry was carried out utilizing 15 antibodies with identified affiliation to radioresistance in PCA in vitro. ELISA was used for validation of chosen markers in serum.

Outcomes: 

Androgen receptor (AR) was overexpressed in most radio-recurrent PCA (89.7%) and in most major high-risk Gleason PCA (87.8%; p = 0.851), whereas solely 67.3% of the low-risk group confirmed an expression (p = 0.017). Contemplating the best Gleason sample in major PCA, aldo-keto reductase household 1 member C3 (AKR1C3) was most equally expressed by sufferers with radio-recurrent PCA and sufferers with Gleason patterns Four and 5 (p = 0.827 and p = 0.893) in comparison with Gleason sample 3 (p = 0.20). These findings had been supported by ELISA.

Conclusion:

That is the primary research to judge protein markers with a purpose to predict radioresistance in PCA. Our outcomes level to AR and AKR1C3 as essentially the most promising markers which may assist stratify sufferers for radiotherapy.

konka-chemica
konka-chemica

Liquid Wicks, Size 15, 200 /pk

W-15 200 WICKS
EUR 22
Description: Liquid Wicks, Size 15, 200 /pk

Human CCL-5 ELISA Kit

EHC0240 96Tests
EUR 625.2

AXYGEN® HORIZONTAL GEL BOX, 15 CM

HGB-15 1/pk
EUR 583.2
Description: Lab Equipment; Axygen Branded EQ

DiagNano Fluorophore Labeled Gold Nanoparticles, 15 nm

GFL-15 1 mL
EUR 1263.6

AXYGEN® GEL TRAY 15 X 15 CM FOR USE WITH 15 CM GEL BOX, UV TRANSPARENT

HGB15-15-GT 1/pk
EUR 94.8
Description: Lab Equipment; Axygen Branded EQ

DiagNano Gold Nanoparticle Passive Conjugation Kit, 15 nm

GPK-15 1 kit
EUR 858

Anti-Human IgG

DB173RTU-15 15 ml
EUR 426
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Human IgG

DB174RTU-15 15 ml
EUR 426
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Normal Rabbit Serum | RS-15-100ML

RS-15-100ML 100 mL
EUR 420
Description:

Normal Rabbit Serum | RS-15-100ML | Immunology Consultants Laboratory

Species Reactivity: Rabbit

Format: Serum

Product Type: Isotype Control

Antibody clonality: Polyclonal

Mouse CCL-5 ELISA Kit

EMC0240 96Tests
EUR 625.2

Sheep CCL-5 ELISA Kit

ESC0240 96Tests
EUR 625.2

Monkey CCL-5 ELISA Kit

EMKC0240 96Tests
EUR 625.2

Rat CCL-5 ELISA Kit

ERC0240 96Tests
EUR 625.2

Rabbit CCL-5 ELISA Kit

ERTC0240 96Tests
EUR 625.2

Porcine CCL-5 ELISA Kit

EPC0240 96Tests
EUR 625.2

Goat CCL-5 ELISA Kit

EGTC0240 96Tests
EUR 625.2

Bovine CCL-5 ELISA Kit

EBC0240 96Tests
EUR 625.2

Canine CCL-5 ELISA Kit

ECC0240 96Tests
EUR 625.2

Chicken CCL-5 ELISA Kit

ECKC0240 96Tests
EUR 625.2

Anserini CCL-5 ELISA Kit

EAC0240 96Tests
EUR 625.2

Anti-Human Kappa Light Chain

DB037RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Human Kappa Light Chain

DB038RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Human Lambda Light Chain

DB039RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Sulfur 15 ug/g (15 PPM) for AA and ICP 100 grams in no.2 Diesel Fuel

SDFS-15-Y 100ML
EUR 102.6

Polyclonal Goat anti-GST α-form

GST-ANTI-1 50 uL
EUR 336

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 336

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 336

Guinea Pig CCL-5 ELISA Kit

EGC0240 96Tests
EUR 625.2

DiagNano Gold Nanoparticle Medium Covalent Conjugation Kit, 15 nm

GCK-M-15 1 kit
EUR 908.4

DiagNano Fluorophore Labeled Gold Nanoparticles, 15 nm, Cellular Uptake

GFL-15-CU 1mL
EUR 1638

Anti-iNOS

DB003RTU-15 15 ml
EUR 513.6
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-p53

DB026RTU-15 15 ml
EUR 405.6
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD5

DB027RTU-15 15 ml
EUR 496.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD20

DB041RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD45

DB042RTU-15 15 ml
EUR 405.6
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD163

DB045RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Melanosome

DB049RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD10

DB057RTU-15 15 ml
EUR 496.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD117

DB062RTU-15 15 ml
EUR 405.6
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD1a

DB071RTU-15 15 ml
EUR 496.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD3

DB082RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD8

DB085RTU-15 15 ml
EUR 496.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-EGFR

DB092RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD7

DB114RTU-15 15 ml
EUR 513.6
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-MSH2

DB115RTU-15 15 ml
EUR 480
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-p63

DB134RTU-15 15 ml
EUR 416.4
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD23

DB135RTU-15 15 ml
EUR 514.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Desmin

DB148RTU-15 15 ml
EUR 416.4
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD34

DB151RTU-15 15 ml
EUR 416.4
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-p16

DB152RTU-15 15 ml
EUR 416.4
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Synaptophysin

DB156RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Braf

DB159RTU-15 15 ml
EUR 850.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-p60

DB203RTU-15 15 ml
EUR 416.4
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

anti-Claudin 15

YF-PA18066 50 ug
EUR 435.6
Description: Mouse polyclonal to Claudin 15

anti-Claudin 15

YF-PA18067 100 ug
EUR 483.6
Description: Rabbit polyclonal to Claudin 15

anti-Kallikrein 15

YF-PA19752 50 ul
EUR 435.6
Description: Mouse polyclonal to Kallikrein 15

anti-Calpain 15

YF-PA24745 50 ul
EUR 400.8
Description: Mouse polyclonal to Calpain 15

anti-Cytokeratin 15

YF-PA12886 100 ul
EUR 483.6
Description: Rabbit polyclonal to Cytokeratin 15

anti-Cytokeratin 15

YF-PA12887 100 ug
EUR 483.6
Description: Rabbit polyclonal to Cytokeratin 15

Anti-b-actin

DB001RTU-15 15 ml
EUR 318
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Melan A

DB050RTU-15 15 ml
EUR 362.4
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 7

DB051RTU-15 15 ml
EUR 370.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-S-100

DB055RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cyclin D1

DB066RTU-15 15 ml
EUR 496.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Ki-67

DB070RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-TTF-1

DB089RTU-15 15 ml
EUR 513.6
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 8

DB098RTU-15 15 ml
EUR 370.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 14

DB099RTU-15 15 ml
EUR 362.4
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 16

DB100RTU-15 15 ml
EUR 362.4
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 17

DB101RTU-15 15 ml
EUR 362.4
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 18

DB102RTU-15 15 ml
EUR 318
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 19

DB103RTU-15 15 ml
EUR 318
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-C3d complement

DB106RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-C4d complement

DB107RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Ki-67

DB111RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 20

DB119RTU-15 15 ml
EUR 370.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Chromogranin A

DB158RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-P504S (AMACR)

DB208RTU-15 15 ml
EUR 408
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Human GCDFP-15 antibody

STJ16100371 1 mL
EUR 1147.2

Anti-ER (Estrogen Receptor)

DB053RTU-15 15 ml
EUR 487.2
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-PR (Progesterone Receptor)

DB059RTU-15 15 ml
EUR 513.6
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-EBV/LMP-1

DB060RTU-15 15 ml
EUR 513.6
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-EBV/LMP-1

DB061RTU-15 15 ml
EUR 513.6
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Cytokeratin 5/6

DB097RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-PR (Progesterone Receptor)

DB108RTU-15 15 ml
EUR 513.6
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-PR (Progesterone Receptor)

DB109RTU-15 15 ml
EUR 513.6
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-p16 (mouse monoclonal)

DB253RTU-15 15 ml
EUR 416.4
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

TruStrip Sample Transfer Strips, 15-ul, 50/Pk (without sample tracking dye)

STS-15-50 1 Pk Ask for price

TruStrip Sample Transfer Strips, 15-ul, 50/Pk (with sample tracking dye)

STSD-15-50 1 Pk Ask for price

Anti-PLAP (Placental Alkaline Phosphatase)

DB047RTU-15 15 ml
EUR 318
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-EMA (CD227, Mucin-1)

DB048RTU-15 15 ml
EUR 318
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Alpha Smooth Muscle Actin

DB147RTU-15 15 ml
EUR 416.4
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

IL-15, Interleukin-15, human

RC212-26 2ug
EUR 125.26

Nori® Porcine 6-Plex ELISA Kits-CCL

GR224026 96-well
EUR 754.8

Nori® Equine 6-Plex ELISA Kits-CCL

GR225026 96-well
EUR 754.8

Nori® Canine 6-Plex ELISA Kits-CCL

GR226026 96-well
EUR 754.8

Nori® Bovine 6-Plex ELISA Kits-CCL

GR228026 96-well
EUR 754.8

Anti-Human IgG

DB-173-RTU-15 15 ml
EUR 426
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-Human IgG

DB-174-RTU-15 15 ml
EUR 426
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Goat IgG Secondary antibody Clone: pAb to UltraPolymer Goat Anti-Human IgG (H&L) HRP

A1278-15 15 ml
EUR 386.4
Description: Goat IgG Secondary antibody Clone: pAb against UltraPolymer Goat Anti-Human IgG (H&L) HRPfor application in IHC.The immunogen is Human IgG (H&L).This antibody can be used for detection of the target molecule in samples from Human.

anti- Cytokeratin 15 antibody

FNab02198 100µg
EUR 606.3
Description: Antibody raised against Cytokeratin 15

anti- Cytokeratin 15 antibody

FNab02199 100µg
EUR 658.5
Description: Antibody raised against Cytokeratin 15

Anti-Cytokeratin 15 Antibody

A06791 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for Cytokeratin 15 Antibody (KRT15) detection.tested for WB in Human, Mouse, Rat, Monkey.

Anti-DHHC-15 Antibody

A12099 100ul
EUR 476.4
Description: Rabbit Polyclonal Antibody for DHHC-15 Antibody (ZDHHC15) detection. Tested with WB in Human.

Anti-GDF-15 Antibody

A2038-100 100 µl
EUR 502.8

Anti-MMP-15 Antibody

A06396 100ul
EUR 476.4
Description: Rabbit Polyclonal MMP-15 Antibody. Validated in WB and tested in Human, Mouse.

anti-p53 (Ab-15)

LF-PA20358 100 ul
EUR 400.8
Description: Rabbit polyclonal to p53

anti-CDC2 (Ab-15)

LF-PA20070 100 ul
EUR 400.8
Description: Rabbit polyclonal to CDC2

anti-HSP27 (Ab-15)

LF-PA20219 100 ul
EUR 400.8
Description: Rabbit polyclonal to HSP27

Anti-Cytokeratin 15 antibody

PAab02198 100 ug
EUR 426

Anti-GCDFP-15 antibody

STJ16100370 1 mL
EUR 975.6

Anti-GCDFP-15 antibody

STJ180109 0.1 ml
EUR 255.6

Anti-GCDFP-15 antibody

STJ180290 0.1 ml
EUR 254.4

Anti-CK-15 antibody

STJ190030 200 µl
EUR 236.4
Description: Unconjugated Mouse monoclonal to CK-15 (5A1)

Anti-MMP-15 antibody

STJ94276 200 µl
EUR 236.4
Description: Rabbit polyclonal to MMP-15.

Anti-PEA-15 antibody

STJ95018 200 µl
EUR 236.4
Description: Rabbit polyclonal to PEA-15.

Anti-PEA-15 antibody

STJ95019 200 µl
EUR 236.4
Description: Rabbit polyclonal to PEA-15.

Anti-PEA-15 antibody

STJ95020 200 µl
EUR 236.4
Description: Rabbit polyclonal to PEA-15.

Anti-BMP-15 antibody

STJ97345 200 µl
EUR 236.4
Description: Rabbit polyclonal to BMP-15.

Anti-Cytokeratin 15 antibody

STJ92628 200 µl
EUR 236.4
Description: Rabbit polyclonal to Cytokeratin 15.

Anti-DHHC-15 antibody

STJ92707 200 µl
EUR 236.4
Description: Rabbit polyclonal to DHHC-15.

Anti-GDF-15 antibody

STJ93253 200 µl
EUR 236.4
Description: Rabbit polyclonal to GDF-15.

Anti-IL-15 antibody

STJ99006 200 µl
EUR 236.4
Description: Rabbit polyclonal to IL-15.

Anti-Cytokeratin 15 antibody

STJ97982 100 µl
EUR 280.8
Description: Mouse monoclonal to Cytokeratin 15.

anti-15 Lipoxygenase 1

YF-PA10168 100 ug
EUR 483.6
Description: Rabbit polyclonal to 15 Lipoxygenase 1

anti-Protease Inhibitor 15

YF-PA18816 50 ul
EUR 435.6
Description: Mouse polyclonal to Protease Inhibitor 15

Anti-Calpain 15 (4E2)

YF-MA15522 100 ug
EUR 435.6
Description: Mouse monoclonal to Calpain 15

Anti-Calpain 15 (2H7)

YF-MA15523 100 ug
EUR 435.6
Description: Mouse monoclonal to Calpain 15

Anti-C-erbB-2 (Her-2/neu)

DB094RTU-15 15 ml
EUR 424.8
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

AXYGEN® 10-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-10-15 1/pk
EUR 72
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 12-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-12-15 1/pk
EUR 72
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 20-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-20-15 1/pk
EUR 72
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 35-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-35-15 1/pk
EUR 82.8
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 8-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-8-15 1/pk
EUR 82.8
Description: Lab Equipment; Axygen Branded EQ

UltraPolymer Goat Anti-Rabbit IgG (H&L) HRP

A1274-15
EUR 385.2

UltraPolymer Goat Anti-Mouse IgG (H&L) HRP

A1275-15
EUR 385.2

UltraPolymer Donkey Anti-Goat IgG (H&L) HRP

A1276-15
EUR 385.2

UltraPolymer Goat Anti-Rat IgG (H&L) HRP

A1277-15
EUR 405.6

UltraPolymer Donkey Anti-Sheep IgG (H&L) HRP

A1279-15
EUR 385.2

T3 (Triiodothyronine) ELISA test

15 96T/Box Ask for price
Description: ELISA based test for quantitative detection of T3 (Triiodothyronine)

Anti-CD15

DB211-RTU-15 15 ml
EUR 426
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD21

DB213-RTU-15 15 ml
EUR 426
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Anti-CD57

DB216-RTU-15 15 ml
EUR 426
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)

Recombinant Human Interleukin-15/IL-15

C016-10ug 10ug
EUR 242.4
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.

Recombinant Human Interleukin-15/IL-15

C016-1mg 1mg
EUR 2203.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.

Recombinant Human Interleukin-15/IL-15

C016-500ug 500ug
EUR 1557.6
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.

Recombinant Human Interleukin-15/IL-15

C016-50ug 50ug
EUR 595.2
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.

Human Interleukin-15 (IL-15) Antibody

30145-05111 150 ug
EUR 313.2

UltraPolymer Goat Anti-Rabbit/Mouse IgG (H&L) HRP Cocktail

A1280-15
EUR 385.2

Anti-Dimethyl Histone H3 (Lys14) Rabbit Monoclonal Antibody, Clone#RM165

M06819-15 100ug
EUR 561.6
Description: Anti-Dimethyl Histone H3 (Lys14) Rabbit Monoclonal Antibody, Clone#RM165 tested in WB, ELISA, Multiplex, reactive to All Vertebrates

AXYGEN® 14-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-14MC-15 1/pk
EUR 75.6
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 16-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-16MC-15 1/pk
EUR 72
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 18-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-18MC-15 1/pk
EUR 72
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 28-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-28MC-15 1/pk
EUR 74.4
Description: Lab Equipment; Axygen Branded EQ

AXYGEN® 30-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS

HGB15-30MC-15 1/pk
EUR 74.4
Description: Lab Equipment; Axygen Branded EQ

MicroMesh: Box of 20 with 80 micron diameter mesh and 15 micron apertures; mounted on 18 mm rods

M3-L18SP-15 20 MOUNTS
EUR 112
Description: MicroMesh: Box of 20 with 80 micron diameter mesh and 15 micron apertures; mounted on 18 mm rods

Nori® Porcine CCL-2/MCP-1 ELISA Kit

GR113217 96-well
EUR 553.2

Nori® Ovine CCL-2/MCP-1 ELISA Kit

GR116154 96-well
EUR 553.2

Rabbit Anti Human Interleukin-15 Polyclonal Antibody

CPBT-65643RH 0.1 mg
EUR 1057.2

Mouse Monoclonal Anti-Human Interleukin-15 IgG

AB-11510 100 ug
EUR 416.4

Purified Anti-human CD172a Antibody *15-414*

11720000 100 ug
EUR 365

APC Anti-human CD172a Antibody *15-414*

117201B0 25 tests
EUR 383

APC Anti-human CD172a Antibody *15-414*

117201B1 100 tests
EUR 995

APC Anti-human CD172a Antibody *15-414*

117201B2 500 tests
EUR 2984

FITC Anti-human CD172a Antibody *15-414*

117201G0 100 tests
EUR 547

FITC Anti-human CD172a Antibody *15-414*

117201G1 500 tests
EUR 2051

TRITC Anti-human CD172a Antibody *15-414*

117201H0 100 tests
EUR 547

TRITC Anti-human CD172a Antibody *15-414*

117201H1 500 tests
EUR 2051

PacBlue Anti-human CD172a Antibody *15-414*

117201I0 100 tests
EUR 547

PacBlue Anti-human CD172a Antibody *15-414*

117201I1 500 tests
EUR 2051

PacOrange Anti-human CD172a Antibody *15-414*

117201J0 100 tests
EUR 547

PacOrange Anti-human CD172a Antibody *15-414*

117201J1 500 tests
EUR 2051

PE Anti-human CD172a Antibody *15-414*

117201K0 25 tests
EUR 383

PE Anti-human CD172a Antibody *15-414*

117201K1 100 tests
EUR 995

PE Anti-human CD172a Antibody *15-414*

117201K2 500 tests
EUR 2984

PerCP Anti-human CD172a Antibody *15-414*

117201S0 25 tests
EUR 383

PerCP Anti-human CD172a Antibody *15-414*

117201S1 100 tests
EUR 995

PerCP Anti-human CD172a Antibody *15-414*

117201S2 500 tests
EUR 2984

Purified Anti-human CD206 Antibody *15-2*

12060000 100 ug
EUR 365

APC Anti-human CD206 Antibody *15-2*

120601B0 25 tests
EUR 383

APC Anti-human CD206 Antibody *15-2*

120601B1 100 tests
EUR 995

APC Anti-human CD206 Antibody *15-2*

120601B2 500 tests
EUR 2984

FITC Anti-human CD206 Antibody *15-2*

120601G0 100 tests
EUR 547

FITC Anti-human CD206 Antibody *15-2*

120601G1 500 tests
EUR 2051

The ribotoxin-like protein Ostreatin from Pleurotus ostreatus fruiting our bodies: Affirmation of a novel ribonuclease household expressed in basidiomycetes

Fungi produce a number of toxins energetic towards crops, animal or people. Amongst them, ribotoxins are enzymes that particularly assault ribosomes irreparably compromising protein synthesis, helpful as pesticides or as anticancer brokers. Right here, a novel ribotoxin from the edible mushroom Pleurotus ostreatus has been purified and characterised.

This ribotoxin, named Ostreatin, is a particular ribonuclease releasing α-fragment when incubated with yeast or rabbit ribosomes. Ostreatin exhibits IC50 of 234 pM in rabbit reticulocyte lysate, and metallic dependent endonuclease exercise. Following the completion of Ostreatin major construction, we ascertained that this toxin is homologous to Ageritin, the primary ribotoxin-like protein from the basidiomycete Agrocybe aegerita, with which it shares 38.8% amino acid sequence identification.

 Ostreatin consists of 131 amino acid residues with an experimental molecular mass of 14,263.51 Da ([M+H+]+). Homology modeling revealed that Ostreatin and Ageritin share an analogous fold by which the widespread catalytic triad is conserved.

Purified Ostreatin lacks N-terminal and C-terminal peptides, which as an alternative are current within the Ostreatin coding sequence. Such peptides are in all probability concerned in protein sorting and for this they might be eliminated. Our findings affirm the presence of ribotoxin-like proteins in basidiomycetes edible mushrooms, that we suggest as novel instrument for biotechnological functions.

Characterization of differentially expressed plasma  proteins in sufferers with acute myocardial infarction

Acute myocardial infarction (AMI) stays a number one reason for morbidity and mortality worldwide. Novel biomarkers are wanted to establish NSTEMI in AMI sufferers. The research goal was to make use of proteomics to establish novel plasma biomarkers for STEMI and NSTEMI sufferers. iTRAQ evaluation was carried out on pooled samples from Eight wholesome controls and 12 STEMI and 12 NSTEMI sufferers.

 Bioinformatics evaluation recognized 95 differentially expressed proteins that had been differentially expressed within the plasma of AMI sufferers and wholesome controls; 28 of those proteins had been present in STEMI/Con (22 upregulated and 6 downregulated), 48 in NSTEMI/Con (12 upregulated and 36 downregulated), and 44 in NSTEMI/STEMI (11 upregulated and 33 downregulated). Protein community evaluation was then carried out utilizing STRING software program.

Practical evaluation revealed that the recognized plasma proteins had been primarily concerned with carbon metabolism, toll-like receptor signaling pathway, and hypertrophic cardiomyopathy. 9 of the proteins (SSA1, MDH1, FCN2, GPI, S100A8, LBP, vinculin, VDBP, and RBP4) that modified ranges throughout AMI development had been additional validated by ELISA. The constructed plasma proteome may mirror the AMI pathogenesis molecular mechanisms and supply a technique for the early identification of NSTEMI in AMI sufferers. SIGNIFICANCE:

The goal of this research was to make use of proteomics to establish novel predictive plasma biomarkers for sufferers with acute myocardial infarction (AMI), which might enable for both identification of people liable to an infarction, and early identification of NSTEMI in sufferers with AMI. Utilizing an strategy that mixed iTRAQ with LC-MS/MS, we discovered 95 proteins that confirmed vital variations in expression ranges among the many AMI sufferers and wholesome controls.

The proteins SSA1, MDH1, FCN2, GPI, S100A8, LBP, vinculin, VDBP, and RBP4 had been discovered to play essential roles within the pathogenesis of AMI. Utilizing bioinformatics evaluation, we discovered that dysregulation of carbon metabolism, toll-like receptor signaling pathway, and hypertrophic cardiomyopathy would be the main driving forces for cardiac harm throughout myocardial infarction.

Nonetheless, additional investigations are wanted to confirm the mechanisms concerned within the improvement of AMI particularly NSTEMI. Taken collectively, our findings lay the muse for understanding the molecular mechanisms underlying the pathogenic processes of AMI, and recommend potential functions for particular biomarkers in early prognosis and willpower of prognosis.

Accuris Taq Master Mix

PR1001-200 1 PC
EUR 145.94

Accuris Taq Master Mix

PR1001-S 1 PC
EUR 83.75

2 × Taq Plus Master Mix

P211-01 5 ml
EUR 160.8

2 × Taq Plus Master Mix

P211-02 15 ml
EUR 231.6

2 × Taq Plus Master Mix

P211-03 50 ml
EUR 466.8

2 × Rapid Taq Master Mix

P222-01 5 ml (5×1ml)
EUR 144

2 × Rapid Taq Master Mix

P222-02 15 ml (15×1ml)
EUR 183.6

2 × Rapid Taq Master Mix

P222-03 50 ml (50 x 1 ml)
EUR 308.4

2 × Rapid Taq Master Mix

P222-04 50 ml (10×5ml)
EUR 308.4

Accuris Taq Plus Master Mix

PR1001-TP-1000 1 PC
EUR 992.89

Accuris Taq Plus Master Mix

PR1001-TP-200 1 PC
EUR 291.41

Accuris Taq Plus Master Mix

PR1001-TP-S 1 PC
EUR 83.75

2× EpiArt HS Taq Master Mix

EM201-01 1ml
EUR 174

2× EpiArt HS Taq Master Mix

EM201-02 5 ml (5×1ml)
EUR 363.6

2× EpiArt HS Taq Master Mix

EM201-03 15 ml (15×1ml)
EUR 770.4

2 × Taq Master Mix (Dye Plus)

P112-01 5 ml
EUR 140.4

2 × Taq Master Mix (Dye Plus)

P112-02 15 ml
EUR 175.2

2 × Taq Master Mix (Dye Plus)

P112-03 50 ml
EUR 283.2

Accuris Hot Start Taq Master Mix

PR1001-HS-1000 1 PC
EUR 589.04

Accuris Hot Start Taq Master Mix

PR1001-HS-200 1 PC
EUR 203.36

Accuris Taq Master Mix Red Dye

PR1001-R-1000 1 PC
EUR 360.31

Accuris Taq Master Mix Red Dye

PR1001-R-200 1 PC
EUR 145.94

Accuris Taq Master Mix Red Dye

PR1001-R-S 1 PC
EUR 83.75

Taq PCR Master Mix (2X, Blue Dye)

BS9295 1ml
EUR 101.76

Taq PCR Master Mix (2X, Blue Dye)

BS9296 5ml
EUR 227.04

Taq PCR Master Mix (2X, Red Dye)

BS9297 1ml
EUR 101.76

Taq PCR Master Mix (2X, Red Dye)

BS9298 5ml
EUR 227.04

2×Taq PCR Master Mix(with dye)

K1034-1 1 ml
EUR 87.6

2×Taq PCR Master Mix(with dye)

K1034-100 100×1 ml
EUR 950.4

2×Taq PCR Master Mix(with dye)

K1034-20 20×1 ml
EUR 338.4

2×Taq PCR Master Mix(with dye)

K1034-5 5×1 ml
EUR 142.8

2×Taq PCR Master Mix(with dye)

K1034-50 50×1 ml
EUR 616.8

2 × Taq Plus Master Mix (Dye Plus)

P212-01 5 ml
EUR 159.6

2 × Taq Plus Master Mix (Dye Plus)

P212-02 15 ml
EUR 231.6

2 × Taq Plus Master Mix (Dye Plus)

P212-03 50 ml
EUR 466.8

2× EpiArt HS Taq Master Mix (Dye Plus)

EM202-01 1ml
EUR 174

2× EpiArt HS Taq Master Mix (Dye Plus)

EM202-02 5 ml (5×1ml)
EUR 363.6

2× EpiArt HS Taq Master Mix (Dye Plus)

EM202-03 15 ml (15×1ml)
EUR 770.4

2 × Taq Plus Master Mix II (Dye Plus)

P213-01 5 ml
EUR 160.8

2 × Taq Plus Master Mix II (Dye Plus)

P213-02 15 ml
EUR 231.6

2 × Taq Plus Master Mix II (Dye Plus)

P213-03 50 ml
EUR 466.8

Accuris Hot Start Taq Master Mix Red Dye

PR1001-HSR-1000 1 PC
EUR 589.04

Accuris Hot Start Taq Master Mix Red Dye

PR1001-HSR-200 1 PC
EUR 203.36

Accuris Hot Start Taq Master Mix Red Dye

PR1001-HSR-S 1 PC
EUR 83.75

Green Taq Mix

P131-01 5 ml
EUR 142.8

Green Taq Mix

P131-02 15 ml
EUR 180

Green Taq Mix

P131-03 50 ml
EUR 297.6

Jade? Master Mix

M1105-500
EUR 529.2

Taqman Master Mix

M1121-500
EUR 529.2

Taqman Master Mix-iCycler

M1122-500
EUR 529.2

Taqman Master Mix-ROX

M1124-500
EUR 529.2

Taqman Master Mix-Multiplex

M1125-500
EUR 529.2

amfiSure PCR Master Mix

P0311-010 2x50 rxns
EUR 151.2

amfiSure PCR Master Mix

P0311-025 5X50 rxns
EUR 198

amfiSure PCR Master Mix

P0311-050 10X50 rxns
EUR 262.8

amfiSure PCR Master Mix

P0311-100 10x1ml
EUR 343.2

amfiSure PCR Master Mix

P0311-125 15X50 rxns
EUR 333.6

amfiSure PCR Master Mix

P0311-200 20x1ml
EUR 562.8

amfiSure PCR Master Mix

P0311-250 50x50 rxns
EUR 902.4

amfiSure PCR Master Mix

P0311-500 100x50 rxns
EUR 1509.6

amfiXpand PCR Master Mix

P0331-010 2X50 rxns
EUR 181.2

amfiXpand PCR Master Mix

P0331-025 5X50 rxns
EUR 327.6

amfiXpand PCR Master Mix

P0331-050 10X50 rxns
EUR 537.6

amfiXpand PCR Master Mix

P0331-250 50x50 rxns
EUR 2247.6

2 × AceTaq Master Mix

P411-01 1 ml
EUR 142.8

2 × AceTaq Master Mix

P411-02 5 ml
EUR 189.6

2 × AceTaq Master Mix

P411-03 15 ml
EUR 314.4

Volatile Organics Mix

60-BIG-MIX 1ML
EUR 120.84

5 Component Mix

AOAC-MIX-1 EACH
EUR 117.42

Seamless cloning Master Mix (Kit)

B632219 40RXN, 40prep
EUR 319.96

Taqman Master Mix-Low ROX

M1123-500
EUR 529.2

amfiSure Prime PCR Master Mix

P1311-025 5X50 rxns
EUR 193.2

amfiSure Prime PCR Master Mix

P1311-050 10X50 rxns
EUR 262.8

amfiSure Prime PCR Master Mix

P1311-125 15X50 rxns
EUR 327.6

amfiSure Prime PCR Master Mix

P1311-250 50x50 rxns
EUR 886.8

amfiSure Prime PCR Master Mix

P1311-500 100x50 rxns
EUR 1485.6

SYBR Green qPCR Master Mix

HY-K0501 5 mL (500 rxns)
EUR 315.6

RT Master Mix for qPCR

HY-K0510 1 mL (100 rxns)
EUR 349.2

amfiSure Advanced PCR Master Mix

P2311-025 5X50 rxns
EUR 198

amfiSure Advanced PCR Master Mix

P2311-050 10X50 rxns
EUR 267.6

amfiSure Advanced PCR Master Mix

P2311-125 15X50 rxns
EUR 338.4

amfiSure Advanced PCR Master Mix

P2311-250 50x50 rxns
EUR 902.4

amfiSure Advanced PCR Master Mix

P2311-500 100x50 rxns
EUR 1534.8

2 × Vazyme LAmp Master Mix

P311-01 1 ml
EUR 164.4

2 × Vazyme LAmp Master Mix

P311-02 5 ml
EUR 254.4

2 × Vazyme LAmp Master Mix

P311-03 15 ml
EUR 481.2

2 × Phanta Max Master Mix

P515-01 1 ml
EUR 174

2 × Phanta Max Master Mix

P515-02 5 ml
EUR 322.8

2 × Phanta Max Master Mix

P515-03 15 ml
EUR 690

AceQ qPCR Probe Master Mix

Q112-02 500 rxn (20 μl/rxn)
EUR 265.2

AceQ qPCR Probe Master Mix

Q112-03 2500 rxn (20 μl/rxn)
EUR 775.2

AceQ U+ Probe Master Mix

Q113-02 500 rxn (20 μl/rxn)
EUR 320.4

AceQ U+ Probe Master Mix

Q113-03 2500 rxn (20 μl/rxn)
EUR 1010.4

amfiRivert cDNA Synthesis Master Mix

R5101-050 50 rxns
EUR 498

amfiRivert cDNA Synthesis Master Mix

R5101-100 2X50 rxns
EUR 1016.4

amfiRivert cDNA Synthesis Master Mix

R5101-200 4X50 rxns
EUR 1453.2

Semi-volatile Organics Mix

76-BIG-MIX 1ML
EUR 150.48

Taq 2x PCR Mix 100 rxn

BA01501 100rxn
EUR 112.8
Description: High quality Taq polymerase for different PCR variations and downstream applications.

Taq 5x PCR Mix 12.5 mM

BT10402 250rxn
EUR 130.8
Description: High quality Taq polymerase for different PCR variations and downstream applications.

Volatile Organics Mix (76 Components)

8260-BIG-MIX 1ML
EUR 296.4

Fast Probe Master Mix (200 rxn)

31005 2x1ML
EUR 280.8
Description: Minimum order quantity: 1 unit of 2x1ML

Fast Probe Master Mix (500 rxn)

31005-1 5x1ML
EUR 559.2
Description: Minimum order quantity: 1 unit of 5x1ML

Fast Probe Master Mix (5000 rxn)

31005-2 50x1ML
EUR 4645.2
Description: Minimum order quantity: 1 unit of 50x1ML

Pfu 2x Master Mix - 200 Reactions

3326 1/EA
EUR 360

2x SYBR Green qPCR Master Mix

B21202 5 mL
EUR 268.8
Description: Our 2x SYBR Green qPCR master mix performs toe to toe in all qPCR assays with the most well known brands on the market but surpases them significantly in cost-efficiency.

2x SYBR Green qPCR Master Mix

B21203 25 mL
EUR 1027.2
Description: Our 2x SYBR Green qPCR master mix performs toe to toe in all qPCR assays with the most well known brands on the market but surpases them significantly in cost-efficiency.

PCR-EZ D-PCR MASTER MIX

BS294 100RXN, 100prep
EUR 112.2

2 × AceTaq Master Mix (Dye Plus)

P412-01 1 ml
EUR 142.8

2 × AceTaq Master Mix (Dye Plus)

P412-02 5 ml
EUR 189.6

2 × AceTaq Master Mix (Dye Plus)

P412-03 15 ml
EUR 314.4

amfiSure ONE PCR Master Mix(2X)

P7000-005 5x1 ml
EUR 262.8

amfiSure ONE PCR Master Mix(2X)

P7000-010 10x1 ml
EUR 380.4

amfiSure ONE PCR Master Mix(2X)

P7000-050 50x1 ml
EUR 1453.2

amfiSure ONE PCR Master Mix(2X)

P7000-100 100x1 ml
EUR 2522.4

Maximo Dry-Master Mix (Lyophilized Polymerase)

S295 192 rcs (20µl, in plates or tubes)
EUR 159.6

AceQ Universal SYBR qPCR Master Mix

Q511-02 500 rxn (20 μl/rxn)
EUR 265.2

AceQ Universal SYBR qPCR Master Mix

Q511-03 2500 rxn (20 μl/rxn)
EUR 775.2

ChamQ Universal SYBR qPCR Master Mix

Q711-02 500 rxn (20 μl/rxn)
EUR 265.2

ChamQ Universal SYBR qPCR Master Mix

Q711-03 2500 rxn (20 μl/rxn)
EUR 775.2

ChamQ Geno-SNP Probe Master Mix

Q811-02 500 rxn (20 μl/rxn)
EUR 332.4

ChamQ Geno-SNP Probe Master Mix

Q811-03 2500 rxn (20 μl/rxn)
EUR 1107.6

amfiRivert II cDNA Synthesis Master Mix

R5500-050 50 rxns
EUR 448.8

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