Characterization of differentially expressed plasma proteins in sufferers with acute

konka-chemica

Prediction of Radioresistant Prostate Most cancers Based mostly on Differentially Expressed Proteins

Introduction: 

Though relapses after radiotherapy are widespread in prostate most cancers (PCA) sufferers, these with a excessive threat for radioresistance can’t be recognized previous to therapy but. Subsequently, this proof-of-concept research was carried out to check protein expression profiles of sufferers with radio-recurrent PCA to sufferers handled with major radical prostatectomy separated by Gleason threat teams. We hypothesized that radio-recurrent PCA have an analogous protein expression as high-risk Gleason PCA.

Strategies:

Affected person cohorts consisted of (i) 31 sufferers handled with salvage prostatectomy for regionally recurrent PCA after major radiotherapy and (ii) 94 sufferers handled with major prostatectomy break up right into a Gleason high-risk (≥4 + 3; n = 42 [44.7%]) versus a low-risk group (≤3 + 4; n = 52 [55.3%]). Immunohistochemistry was carried out utilizing 15 antibodies with identified affiliation to radioresistance in PCA in vitro. ELISA was used for validation of chosen markers in serum.

Outcomes: 

Androgen receptor (AR) was overexpressed in most radio-recurrent PCA (89.7%) and in most major high-risk Gleason PCA (87.8%; p = 0.851), whereas solely 67.3% of the low-risk group confirmed an expression (p = 0.017). Contemplating the best Gleason sample in major PCA, aldo-keto reductase household 1 member C3 (AKR1C3) was most equally expressed by sufferers with radio-recurrent PCA and sufferers with Gleason patterns Four and 5 (p = 0.827 and p = 0.893) in comparison with Gleason sample 3 (p = 0.20). These findings had been supported by ELISA.

Conclusion:

That is the primary research to judge protein markers with a purpose to predict radioresistance in PCA. Our outcomes level to AR and AKR1C3 as essentially the most promising markers which may assist stratify sufferers for radiotherapy.

konka-chemica
konka-chemica
Human CCL-5 ELISA Kit
EHC0240 96Tests
EUR 521
AXYGEN® HORIZONTAL GEL BOX, 15 CM
HGB-15 1/pk
EUR 486
Description: Lab Equipment; Axygen Branded EQ
DiagNano Fluorophore Labeled Gold Nanoparticles, 15 nm
GFL-15 1 mL
EUR 1053
AXYGEN® GEL TRAY 15 X 15 CM FOR USE WITH 15 CM GEL BOX, UV TRANSPARENT
HGB15-15-GT 1/pk
EUR 79
Description: Lab Equipment; Axygen Branded EQ
DiagNano Gold Nanoparticle Passive Conjugation Kit, 15 nm
GPK-15 1 kit
EUR 715
Anti-Human IgG
DB173RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Human IgG
DB174RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Goat CCL-5 ELISA Kit
EGTC0240 96Tests
EUR 521
Canine CCL-5 ELISA Kit
ECC0240 96Tests
EUR 521
Chicken CCL-5 ELISA Kit
ECKC0240 96Tests
EUR 521
Bovine CCL-5 ELISA Kit
EBC0240 96Tests
EUR 521
Anserini CCL-5 ELISA Kit
EAC0240 96Tests
EUR 521
Porcine CCL-5 ELISA Kit
EPC0240 96Tests
EUR 521
Rat CCL-5 ELISA Kit
ERC0240 96Tests
EUR 521
Rabbit CCL-5 ELISA Kit
ERTC0240 96Tests
EUR 521
Sheep CCL-5 ELISA Kit
ESC0240 96Tests
EUR 521
Mouse CCL-5 ELISA Kit
EMC0240 96Tests
EUR 521
Monkey CCL-5 ELISA Kit
EMKC0240 96Tests
EUR 521
Anti-Human Kappa Light Chain
DB037RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Human Kappa Light Chain
DB038RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Human Lambda Light Chain
DB039RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Guinea Pig CCL-5 ELISA Kit
EGC0240 96Tests
EUR 521
Polyclonal Goat anti-GST α-form
GST-ANTI-1 50 uL
EUR 280
Polyclonal Goat anti-GST μ-form
GST-ANTI-2 50 uL
EUR 280
Polyclonal Goat anti-GST p-form
GST-ANTI-3 50 uL
EUR 280
Anti-iNOS
DB003RTU-15 15 ml
EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-p53
DB026RTU-15 15 ml
EUR 338
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD5
DB027RTU-15 15 ml
EUR 414
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD20
DB041RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD45
DB042RTU-15 15 ml
EUR 338
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD163
DB045RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Melanosome
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EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD10
DB057RTU-15 15 ml
EUR 414
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD117
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EUR 338
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD1a
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EUR 414
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD3
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EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD8
DB085RTU-15 15 ml
EUR 414
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-EGFR
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EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD7
DB114RTU-15 15 ml
EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-MSH2
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EUR 400
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-p63
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EUR 347
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD23
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EUR 429
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Desmin
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EUR 347
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD34
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EUR 347
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-p16
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EUR 347
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Braf
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EUR 709
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
anti-Cytokeratin 15
YF-PA12886 100 ul
EUR 403
Description: Rabbit polyclonal to Cytokeratin 15
anti-Cytokeratin 15
YF-PA12887 100 ug
EUR 403
Description: Rabbit polyclonal to Cytokeratin 15
anti-Calpain 15
YF-PA24745 50 ul
EUR 334
Description: Mouse polyclonal to Calpain 15
anti-Claudin 15
YF-PA18066 50 ug
EUR 363
Description: Mouse polyclonal to Claudin 15
anti-Claudin 15
YF-PA18067 100 ug
EUR 403
Description: Rabbit polyclonal to Claudin 15
anti-Kallikrein 15
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EUR 363
Description: Mouse polyclonal to Kallikrein 15
DiagNano Fluorophore Labeled Gold Nanoparticles, 15 nm, Cellular Uptake
GFL-15-CU 1mL
EUR 1365
DiagNano Gold Nanoparticle Medium Covalent Conjugation Kit, 15 nm
GCK-M-15 1 kit
EUR 757
Anti-Human GCDFP-15 antibody
STJ16100371 1 mL
EUR 956
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DB001RTU-15 15 ml
EUR 265
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Melan A
DB050RTU-15 15 ml
EUR 302
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Cytokeratin 7
DB051RTU-15 15 ml
EUR 309
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-S-100
DB055RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Cyclin D1
DB066RTU-15 15 ml
EUR 414
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Ki-67
DB070RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-TTF-1
DB089RTU-15 15 ml
EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Cytokeratin 8
DB098RTU-15 15 ml
EUR 309
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Cytokeratin 14
DB099RTU-15 15 ml
EUR 302
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Cytokeratin 16
DB100RTU-15 15 ml
EUR 302
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Cytokeratin 17
DB101RTU-15 15 ml
EUR 302
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Cytokeratin 18
DB102RTU-15 15 ml
EUR 265
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Cytokeratin 19
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EUR 265
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-C3d complement
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EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-C4d complement
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Ki-67
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EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Cytokeratin 20
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Chromogranin A
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-P504S (AMACR)
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-ER (Estrogen Receptor)
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Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-PR (Progesterone Receptor)
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EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-EBV/LMP-1
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EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-EBV/LMP-1
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EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Cytokeratin 5/6
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EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-PR (Progesterone Receptor)
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EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-PR (Progesterone Receptor)
DB109RTU-15 15 ml
EUR 428
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-p16 (mouse monoclonal)
DB253RTU-15 15 ml
EUR 347
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-PLAP (Placental Alkaline Phosphatase)
DB047RTU-15 15 ml
EUR 265
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-EMA (CD227, Mucin-1)
DB048RTU-15 15 ml
EUR 265
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Alpha Smooth Muscle Actin
DB147RTU-15 15 ml
EUR 347
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
anti- Cytokeratin 15 antibody
FNab02198 100µg
EUR 505.25
  • Recommended dilution: WB: 1:500 - 1:2000
  • IHC: 1:50 - 1:200
  • Immunogen: keratin 15
  • Uniprot ID: P19012
  • Gene ID: 3866
  • Research Area: Cancer, Immunology
Description: Antibody raised against Cytokeratin 15
anti- Cytokeratin 15 antibody
FNab02199 100µg
EUR 548.75
  • Recommended dilution: WB: 1:500-1:2000
  • IF: 1:10-1:100
  • Immunogen: keratin 15
  • Uniprot ID: P19012
  • Gene ID: 3866
  • Research Area: Cancer, Immunology
Description: Antibody raised against Cytokeratin 15
Anti-MMP-15 Antibody
A06396 100ul
EUR 397
Description: Rabbit Polyclonal MMP-15 Antibody. Validated in WB and tested in Human, Mouse.
Anti-DHHC-15 Antibody
A12099 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for DHHC-15 Antibody (ZDHHC15) detection. Tested with WB in Human.
Anti-Cytokeratin 15 Antibody
A06791 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Cytokeratin 15 Antibody (KRT15) detection.tested for WB in Human, Mouse, Rat, Monkey.
Anti-Cytokeratin 15 antibody
PAab02198 100 ug
EUR 355
anti-CDC2 (Ab-15)
LF-PA20070 100 ul
EUR 334
Description: Rabbit polyclonal to CDC2
anti-HSP27 (Ab-15)
LF-PA20219 100 ul
EUR 334
Description: Rabbit polyclonal to HSP27
anti-p53 (Ab-15)
LF-PA20358 100 ul
EUR 334
Description: Rabbit polyclonal to p53
Anti-Cytokeratin 15 antibody
STJ92628 200 µl
EUR 197
Description: Rabbit polyclonal to Cytokeratin 15.
Anti-DHHC-15 antibody
STJ92707 200 µl
EUR 197
Description: Rabbit polyclonal to DHHC-15.
Anti-GDF-15 antibody
STJ93253 200 µl
EUR 197
Description: Rabbit polyclonal to GDF-15.
Anti-MMP-15 antibody
STJ94276 200 µl
EUR 197
Description: Rabbit polyclonal to MMP-15.
Anti-PEA-15 antibody
STJ95018 200 µl
EUR 197
Description: Rabbit polyclonal to PEA-15.
Anti-PEA-15 antibody
STJ95019 200 µl
EUR 197
Description: Rabbit polyclonal to PEA-15.
Anti-PEA-15 antibody
STJ95020 200 µl
EUR 197
Description: Rabbit polyclonal to PEA-15.
Anti-BMP-15 antibody
STJ97345 200 µl
EUR 197
Description: Rabbit polyclonal to BMP-15.
Anti-Cytokeratin 15 antibody
STJ97982 100 µl
EUR 234
Description: Mouse monoclonal to Cytokeratin 15.
Anti-IL-15 antibody
STJ99006 200 µl
EUR 197
Description: Rabbit polyclonal to IL-15.
Anti-GCDFP-15 antibody
STJ16100370 1 mL
EUR 813
Anti-GCDFP-15 antibody
STJ180109 0.1 ml
EUR 213
Anti-GCDFP-15 antibody
STJ180290 0.1 ml
EUR 212
Anti-CK-15 antibody
STJ190030 200 µl
EUR 197
Description: Unconjugated Mouse monoclonal to CK-15 (5A1)
Anti-Calpain 15 (4E2)
YF-MA15522 100 ug
EUR 363
Description: Mouse monoclonal to Calpain 15
Anti-Calpain 15 (2H7)
YF-MA15523 100 ug
EUR 363
Description: Mouse monoclonal to Calpain 15
anti-15 Lipoxygenase 1
YF-PA10168 100 ug
EUR 403
Description: Rabbit polyclonal to 15 Lipoxygenase 1
anti-Protease Inhibitor 15
YF-PA18816 50 ul
EUR 363
Description: Mouse polyclonal to Protease Inhibitor 15
Anti-GDF-15 Antibody
A2038-100 100 µl
EUR 419
TruStrip Sample Transfer Strips, 15-ul, 50/Pk (without sample tracking dye)
STS-15-50 1 Pk Ask for price
TruStrip Sample Transfer Strips, 15-ul, 50/Pk (with sample tracking dye)
STSD-15-50 1 Pk Ask for price
Anti-Human IgG
DB-173-RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Human IgG
DB-174-RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-C-erbB-2 (Her-2/neu)
DB094RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
IL-15, Interleukin-15, human
RC212-26 2ug
EUR 104.38
  • Product category: Proteins/Recombinant Proteins/Cytokines
Goat IgG Secondary antibody Clone: pAb to UltraPolymer Goat Anti-Human IgG (H&L) HRP
A1278-15 15 ml
EUR 322
  • What are the applications and the optimal dilutions of the product Antibody against PARP (Clone 10H)for analysis? - Immunocytochemistry : 5-20 ?g/ml | Western Blot (10 ?g/ml using colorimetric methods | <2 ?g/ml for ECL) | Immunoprecipitation and ELI
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Description: Goat IgG Secondary antibody Clone: pAb against UltraPolymer Goat Anti-Human IgG (H&L) HRPfor application in IHC.The immunogen is Human IgG (H&L).This antibody can be used for detection of the target molecule in samples from Human.
UltraPolymer Goat Anti-Rabbit IgG (H&L) HRP
A1274-15
EUR 321
UltraPolymer Goat Anti-Mouse IgG (H&L) HRP
A1275-15
EUR 321
UltraPolymer Donkey Anti-Goat IgG (H&L) HRP
A1276-15
EUR 321
UltraPolymer Goat Anti-Rat IgG (H&L) HRP
A1277-15
EUR 338
UltraPolymer Donkey Anti-Sheep IgG (H&L) HRP
A1279-15
EUR 321
Anti-CD15
DB211-RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD21
DB213-RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-CD57
DB216-RTU-15 15 ml
EUR 355
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
AXYGEN® 10-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS
HGB15-10-15 1/pk
EUR 60
Description: Lab Equipment; Axygen Branded EQ
AXYGEN® 12-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS
HGB15-12-15 1/pk
EUR 60
Description: Lab Equipment; Axygen Branded EQ
AXYGEN® 20-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS
HGB15-20-15 1/pk
EUR 60
Description: Lab Equipment; Axygen Branded EQ
AXYGEN® 35-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS
HGB15-35-15 1/pk
EUR 69
Description: Lab Equipment; Axygen Branded EQ
AXYGEN® 8-WELL COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS
HGB15-8-15 1/pk
EUR 69
Description: Lab Equipment; Axygen Branded EQ
UltraPolymer Goat Anti-Rabbit/Mouse IgG (H&L) HRP Cocktail
A1280-15
EUR 321
Anti-Dimethyl Histone H3 (Lys14) Rabbit Monoclonal Antibody, Clone#RM165
M06819-15 100ug
EUR 468
Description: Anti-Dimethyl Histone H3 (Lys14) Rabbit Monoclonal Antibody, Clone#RM165 tested in WB, ELISA, Multiplex, reactive to All Vertebrates
Mouse Monoclonal Anti-Human Interleukin-15 IgG
AB-11510 100 ug
EUR 347
Rabbit Anti Human Interleukin-15 Polyclonal Antibody
CPBT-65643RH 0.1 mg
EUR 881
anti- 15 Lipoxygenase 2 antibody
FNab00005 100µg
EUR 505.25
  • Recommended dilution: WB: 1:200-1:2000
  • IHC: 1:20-1:200
  • Immunogen: arachidonate 15-lipoxygenase, type B
  • Uniprot ID: O15296
  • Research Area: Metabolism
Description: Antibody raised against 15 Lipoxygenase 2
anti- GCDFP-15/PIP antibody
FNab03381 100µg
EUR 585
  • Recommended dilution: IHC: 1:20-1:200
  • Immunogen: prolactin-induced protein
  • Uniprot ID: P12273
  • Research Area: Cancer, Immunology
Description: Antibody raised against GCDFP-15/PIP
Anti-CDC2 (Ab-15) Antibody
A00209 100ul
EUR 397
Description: Rabbit Polyclonal CDC2 (Ab-15) Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.
Anti-Cytokeratin 15 Monoclonal Antibody
A06791-1 100ul
EUR 397
Description: Mouse Monoclonal Antibody for Cytokeratin 15 Antibody (KRT15) detection.tested for Flow Cytometry, IF, IHC, WB in Human.
Anti-15 Lipoxygenase 2 antibody
PAab00005 100 ug
EUR 355
Anti-GCDFP-15/PIP antibody
PAab03381 100 ug
EUR 412
anti-Stathmin 1 (Ab-15)
LF-PA20485 100 ul
EUR 334
Description: Rabbit polyclonal to Stathmin 1
Anti-IL-15 alpha antibody
STJ93680 200 µl
EUR 197
Description: Rabbit polyclonal to IL-15Ralpha.
Anti-Protease Inhibitor 15 (3B5)
YF-MA11488 100 ug
EUR 363
Description: Mouse monoclonal to Protease Inhibitor 15
Anti-15 Lipoxygenase 1 (1A11)
YF-MA11900 100 ug
EUR 363
Description: Mouse monoclonal to 15 Lipoxygenase 1
Anti-15 Lipoxygenase 2 (4A7)
YF-MA11901 100 ug
EUR 363
Description: Mouse monoclonal to 15 Lipoxygenase 2
Anti-15 Lipoxygenase 1 (3D8)
YF-MA10038 100 ug
EUR 363
Description: Mouse monoclonal to 15 Lipoxygenase 1
T3 (Triiodothyronine) ELISA test
15 96T/Box Ask for price
  • Area of application: Hormone testing
Description: ELISA based test for quantitative detection of T3 (Triiodothyronine)
Anti-PD-L1
DB241-RTU-15 15 ml
EUR 678
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Recombinant Human Interleukin-15/IL-15
C016-10ug 10ug
EUR 202
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
Recombinant Human Interleukin-15/IL-15
C016-1mg 1mg
EUR 1836
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
Recombinant Human Interleukin-15/IL-15
C016-500ug 500ug
EUR 1298
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
Recombinant Human Interleukin-15/IL-15
C016-50ug 50ug
EUR 496
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0.
Human Interleukin-15 (IL-15) Antibody
30145-05111 150 ug
EUR 261
Anti-Human Kappa Light Chain
DB-037-RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Human Kappa Light Chain
DB-038-RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
Anti-Human Lambda Light Chain
DB-039-RTU-15 15 ml
EUR 354
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use)
AXYGEN® 14-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS
HGB15-14MC-15 1/pk
EUR 63
Description: Lab Equipment; Axygen Branded EQ
AXYGEN® 16-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS
HGB15-16MC-15 1/pk
EUR 60
Description: Lab Equipment; Axygen Branded EQ
AXYGEN® 18-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS
HGB15-18MC-15 1/pk
EUR 60
Description: Lab Equipment; Axygen Branded EQ
AXYGEN® 28-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS
HGB15-28MC-15 1/pk
EUR 62
Description: Lab Equipment; Axygen Branded EQ
AXYGEN® 30-WELL MULTI-CHANNEL COMPATIBLE COMB FOR USE WITH 15 CM GEL BOX, 1.5 MM THICKNESS
HGB15-30MC-15 1/pk
EUR 62
Description: Lab Equipment; Axygen Branded EQ
Human IL-15(Interleukin 15) ELISA Kit
EH0177 96T
EUR 476.25
  • Detection range: 15.625-1000 pg/ml
  • Uniprot ID: P40933
  • Alias: IL-15/IL15
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml
Human Interleukin 15(IL-15)ELISA Kit
GA-E0137HM-48T 48T
EUR 289
Human Interleukin 15(IL-15)ELISA Kit
GA-E0137HM-96T 96T
EUR 466
Human Interleukin 15 (IL-15) CLIA Kit
abx195854-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.
Human Interleukin 15,IL-15 ELISA KIT
201-12-0098 96 tests
EUR 440
  • This Interleukin 15 ELISA kit is validated to work with samples from whole blood, serum, plasma and cell culture supernatant.
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.
Human Interleukin 15, IL-15 ELISA KIT
CSB-E04603h-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 15, IL-15 in samples from serum, plasma, tissue homogenates, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Human Interleukin 15, IL-15 ELISA KIT
1-CSB-E04603h
  • EUR 603.00
  • EUR 4247.00
  • EUR 2260.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 15, IL-15 in samples from serum, plasma, tissue homogenates, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Human Interleukin 15,IL-15 ELISA KIT
CN-03216H1 96T
EUR 434
Human Interleukin 15,IL-15 ELISA KIT
CN-03216H2 48T
EUR 284
Human Interleukin-15 (IL-15) ELISA Kit
LF-EK60041 1×96T
EUR 790
Human Interleukin 15(IL-15)ELISA Kit
QY-E04325 96T
EUR 361
IL-15 Interleukin-15 Human Recombinant Protein
PROTP40933 Regular: 10ug
EUR 317
Description: Interleukin-15 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 114 amino acids (and an N-terminal Methionine) and having a molecular mass of 12.8kDa. The IL-15 is purified by proprietary chromatographic techniques.
IL-15, Human
HY-P7034 50ug
EUR 670
1-step Polymer HISTO-STAT; HRP anti Mouse for staining Mouse and Rat antibodies, 250 plus slides
NB312M-15 15 ml
EUR 427
1-step Polymer HISTO-STAT; HRP anti Rat (SecondaryReagent Component) for staining Rat antibodies, 250 plus slides
NB312T-15 15 ml
EUR 427
Anti-15 Lipoxygenase 1/ALOX15 Antibody
PB9073 100ug/vial
EUR 334
Anti-Fibronectin Antibody (monoclonal, FN-15)
MA1116 100ug/vial
EUR 334
Anti-Cytokeratin 15 Rabbit Monoclonal Antibody
M06791-1 100ug/vial
EUR 397
Description: Rabbit Monoclonal Cytokeratin 15 Antibody. Validated in IF, WB and tested in Human, Mouse.

The ribotoxin-like protein Ostreatin from Pleurotus ostreatus fruiting our bodies: Affirmation of a novel ribonuclease household expressed in basidiomycetes

Fungi produce a number of toxins energetic towards crops, animal or people. Amongst them, ribotoxins are enzymes that particularly assault ribosomes irreparably compromising protein synthesis, helpful as pesticides or as anticancer brokers. Right here, a novel ribotoxin from the edible mushroom Pleurotus ostreatus has been purified and characterised.

This ribotoxin, named Ostreatin, is a particular ribonuclease releasing α-fragment when incubated with yeast or rabbit ribosomes. Ostreatin exhibits IC50 of 234 pM in rabbit reticulocyte lysate, and metallic dependent endonuclease exercise. Following the completion of Ostreatin major construction, we ascertained that this toxin is homologous to Ageritin, the primary ribotoxin-like protein from the basidiomycete Agrocybe aegerita, with which it shares 38.8% amino acid sequence identification.

 Ostreatin consists of 131 amino acid residues with an experimental molecular mass of 14,263.51 Da ([M+H+]+). Homology modeling revealed that Ostreatin and Ageritin share an analogous fold by which the widespread catalytic triad is conserved.

Purified Ostreatin lacks N-terminal and C-terminal peptides, which as an alternative are current within the Ostreatin coding sequence. Such peptides are in all probability concerned in protein sorting and for this they might be eliminated. Our findings affirm the presence of ribotoxin-like proteins in basidiomycetes edible mushrooms, that we suggest as novel instrument for biotechnological functions.

Characterization of differentially expressed plasma  proteins in sufferers with acute myocardial infarction

Acute myocardial infarction (AMI) stays a number one reason for morbidity and mortality worldwide. Novel biomarkers are wanted to establish NSTEMI in AMI sufferers. The research goal was to make use of proteomics to establish novel plasma biomarkers for STEMI and NSTEMI sufferers. iTRAQ evaluation was carried out on pooled samples from Eight wholesome controls and 12 STEMI and 12 NSTEMI sufferers.

 Bioinformatics evaluation recognized 95 differentially expressed proteins that had been differentially expressed within the plasma of AMI sufferers and wholesome controls; 28 of those proteins had been present in STEMI/Con (22 upregulated and 6 downregulated), 48 in NSTEMI/Con (12 upregulated and 36 downregulated), and 44 in NSTEMI/STEMI (11 upregulated and 33 downregulated). Protein community evaluation was then carried out utilizing STRING software program.

Practical evaluation revealed that the recognized plasma proteins had been primarily concerned with carbon metabolism, toll-like receptor signaling pathway, and hypertrophic cardiomyopathy. 9 of the proteins (SSA1, MDH1, FCN2, GPI, S100A8, LBP, vinculin, VDBP, and RBP4) that modified ranges throughout AMI development had been additional validated by ELISA. The constructed plasma proteome may mirror the AMI pathogenesis molecular mechanisms and supply a technique for the early identification of NSTEMI in AMI sufferers. SIGNIFICANCE:

The goal of this research was to make use of proteomics to establish novel predictive plasma biomarkers for sufferers with acute myocardial infarction (AMI), which might enable for both identification of people liable to an infarction, and early identification of NSTEMI in sufferers with AMI. Utilizing an strategy that mixed iTRAQ with LC-MS/MS, we discovered 95 proteins that confirmed vital variations in expression ranges among the many AMI sufferers and wholesome controls.

The proteins SSA1, MDH1, FCN2, GPI, S100A8, LBP, vinculin, VDBP, and RBP4 had been discovered to play essential roles within the pathogenesis of AMI. Utilizing bioinformatics evaluation, we discovered that dysregulation of carbon metabolism, toll-like receptor signaling pathway, and hypertrophic cardiomyopathy would be the main driving forces for cardiac harm throughout myocardial infarction.

Nonetheless, additional investigations are wanted to confirm the mechanisms concerned within the improvement of AMI particularly NSTEMI. Taken collectively, our findings lay the muse for understanding the molecular mechanisms underlying the pathogenic processes of AMI, and recommend potential functions for particular biomarkers in early prognosis and willpower of prognosis.

2 × Taq Master Mix

P111-02 15 ml
EUR 146

2 × Taq Master Mix

P111-03 50 ml
EUR 236

Accuris Taq Master Mix

PR1001-1000 1 PC
EUR 300.26
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris Taq Master Mix

PR1001-200 1 PC
EUR 121.62
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris Taq Master Mix

PR1001-S 1 PC
EUR 69.79
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

2 × Taq Plus Master Mix

P211-01 5 ml
EUR 134

2 × Taq Plus Master Mix

P211-02 15 ml
EUR 193

2 × Taq Plus Master Mix

P211-03 50 ml
EUR 389

Accuris Taq Plus Master Mix

PR1001-TP-1000 1 PC
EUR 827.41
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris Taq Plus Master Mix

PR1001-TP-200 1 PC
EUR 242.84
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris Taq Plus Master Mix

PR1001-TP-S 1 PC
EUR 69.79
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

2 × Rapid Taq Master Mix

P222-01 5 ml (5×1ml)
EUR 120

2 × Rapid Taq Master Mix

P222-02 15 ml (15×1ml)
EUR 153

2 × Rapid Taq Master Mix

P222-03 50 ml (50 x 1 ml)
EUR 257

2 × Rapid Taq Master Mix

P222-04 50 ml (10×5ml)
EUR 257

2× EpiArt HS Taq Master Mix

EM201-01 1ml
EUR 145

2× EpiArt HS Taq Master Mix

EM201-02 5 ml (5×1ml)
EUR 303

2× EpiArt HS Taq Master Mix

EM201-03 15 ml (15×1ml)
EUR 642

2 × Taq Master Mix (Dye Plus)

P112-01 5 ml
EUR 117

2 × Taq Master Mix (Dye Plus)

P112-02 15 ml
EUR 146

2 × Taq Master Mix (Dye Plus)

P112-03 50 ml
EUR 236

Accuris Hot Start Taq Master Mix

PR1001-HS-1000 1 PC
EUR 490.87
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris Hot Start Taq Master Mix

PR1001-HS-200 1 PC
EUR 169.47
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris Taq Master Mix Red Dye

PR1001-R-1000 1 PC
EUR 300.26
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris Taq Master Mix Red Dye

PR1001-R-200 1 PC
EUR 121.62
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris Taq Master Mix Red Dye

PR1001-R-S 1 PC
EUR 69.79
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

2×Taq PCR Master Mix(with dye)

K1034-1 1 ml
EUR 73

2×Taq PCR Master Mix(with dye)

K1034-100 100×1 ml
EUR 792

2×Taq PCR Master Mix(with dye)

K1034-20 20×1 ml
EUR 282

2×Taq PCR Master Mix(with dye)

K1034-5 5×1 ml
EUR 119

2×Taq PCR Master Mix(with dye)

K1034-50 50×1 ml
EUR 514

2 × Taq Plus Master Mix (Dye Plus)

P212-01 5 ml
EUR 133

2 × Taq Plus Master Mix (Dye Plus)

P212-02 15 ml
EUR 193

2 × Taq Plus Master Mix (Dye Plus)

P212-03 50 ml
EUR 389

Taq PCR Master Mix (2X, Blue Dye)

BS9295 1ml
EUR 84.8
  • Product category: PCR Related/PCR Premix (qPCR)/qPCR Premix + Taq

Taq PCR Master Mix (2X, Blue Dye)

BS9296 5ml
EUR 189.2
  • Product category: PCR Related/PCR Premix (qPCR)/qPCR Premix + Taq

Taq PCR Master Mix (2X, Red Dye)

BS9297 1ml
EUR 84.8
  • Product category: PCR Related/PCR Premix (qPCR)/qPCR Premix + Taq

Taq PCR Master Mix (2X, Red Dye)

BS9298 5ml
EUR 189.2
  • Product category: PCR Related/PCR Premix (qPCR)/qPCR Premix + Taq

2× EpiArt HS Taq Master Mix (Dye Plus)

EM202-01 1ml
EUR 145

2× EpiArt HS Taq Master Mix (Dye Plus)

EM202-02 5 ml (5×1ml)
EUR 303

2× EpiArt HS Taq Master Mix (Dye Plus)

EM202-03 15 ml (15×1ml)
EUR 642

Hot Start Taq 2x Master Mix - 500 Reactions

3296 1/EA
EUR 268

Accuris Hot Start Taq Master Mix Red Dye

PR1001-HSR-1000 1 PC
EUR 490.87
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris Hot Start Taq Master Mix Red Dye

PR1001-HSR-200 1 PC
EUR 169.47
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

Accuris Hot Start Taq Master Mix Red Dye

PR1001-HSR-S 1 PC
EUR 69.79
  • To order instruments in 115V / US plug please delete the 'E' off the order code.European 2 pin plugs will be supplied as standard, please request UK if required.

2 × Taq Plus Master Mix II (Dye Plus)

P213-01 5 ml
EUR 134

2 × Taq Plus Master Mix II (Dye Plus)

P213-02 15 ml
EUR 193

2 × Taq Plus Master Mix II (Dye Plus)

P213-03 50 ml
EUR 389

Green Taq Mix

P131-01 5 ml
EUR 119

Green Taq Mix

P131-02 15 ml
EUR 150

Green Taq Mix

P131-03 50 ml
EUR 248

Jade? Master Mix

M1105-500
EUR 441

Taqman Master Mix

M1121-500
EUR 441

Taqman Master Mix-iCycler

M1122-500
EUR 441

Taqman Master Mix-ROX

M1124-500
EUR 441

Taqman Master Mix-Multiplex

M1125-500
EUR 441

amfiSure PCR Master Mix

P0311-010 2x50 rxns
EUR 126

amfiSure PCR Master Mix

P0311-025 5X50 rxns
EUR 165

amfiSure PCR Master Mix

P0311-050 10X50 rxns
EUR 219

amfiSure PCR Master Mix

P0311-100 10x1ml
EUR 286

amfiSure PCR Master Mix

P0311-125 15X50 rxns
EUR 278

amfiSure PCR Master Mix

P0311-200 20x1ml
EUR 469

amfiSure PCR Master Mix

P0311-250 50x50 rxns
EUR 752

amfiSure PCR Master Mix

P0311-500 100x50 rxns
EUR 1258

amfiXpand PCR Master Mix

P0331-010 2X50 rxns
EUR 151

amfiXpand PCR Master Mix

P0331-025 5X50 rxns
EUR 273

amfiXpand PCR Master Mix

P0331-050 10X50 rxns
EUR 448

amfiXpand PCR Master Mix

P0331-250 50x50 rxns
EUR 1873

2 × AceTaq Master Mix

P411-01 1 ml
EUR 119

2 × AceTaq Master Mix

P411-02 5 ml
EUR 158

2 × AceTaq Master Mix

P411-03 15 ml
EUR 262

SYBR Green qPCR Master Mix

HY-K0501 5 mL (500 rxns)
EUR 263

RT Master Mix for qPCR

HY-K0510 1 mL (100 rxns)
EUR 291

amfiSure Prime PCR Master Mix

P1311-025 5X50 rxns
EUR 161

amfiSure Prime PCR Master Mix

P1311-050 10X50 rxns
EUR 219

amfiSure Prime PCR Master Mix

P1311-125 15X50 rxns
EUR 273

amfiSure Prime PCR Master Mix

P1311-250 50x50 rxns
EUR 739

amfiSure Prime PCR Master Mix

P1311-500 100x50 rxns
EUR 1238

Taqman Master Mix-Low ROX

M1123-500
EUR 441

amfiSure Advanced PCR Master Mix

P2311-025 5X50 rxns
EUR 165

amfiSure Advanced PCR Master Mix

P2311-050 10X50 rxns
EUR 223

amfiSure Advanced PCR Master Mix

P2311-125 15X50 rxns
EUR 282

amfiSure Advanced PCR Master Mix

P2311-250 50x50 rxns
EUR 752

amfiSure Advanced PCR Master Mix

P2311-500 100x50 rxns
EUR 1279

2 × Vazyme LAmp Master Mix

P311-01 1 ml
EUR 137

2 × Vazyme LAmp Master Mix

P311-02 5 ml
EUR 212

2 × Vazyme LAmp Master Mix

P311-03 15 ml
EUR 401

2 × Phanta Max Master Mix

P515-01 1 ml
EUR 145

2 × Phanta Max Master Mix

P515-02 5 ml
EUR 269

2 × Phanta Max Master Mix

P515-03 15 ml
EUR 575

AceQ qPCR Probe Master Mix

Q112-02 500 rxn (20 μl/rxn)
EUR 221

AceQ qPCR Probe Master Mix

Q112-03 2500 rxn (20 μl/rxn)
EUR 646

AceQ U+ Probe Master Mix

Q113-02 500 rxn (20 μl/rxn)
EUR 267

AceQ U+ Probe Master Mix

Q113-03 2500 rxn (20 μl/rxn)
EUR 842

amfiRivert cDNA Synthesis Master Mix

R5101-050 50 rxns
EUR 415

amfiRivert cDNA Synthesis Master Mix

R5101-100 2X50 rxns
EUR 847

amfiRivert cDNA Synthesis Master Mix

R5101-200 4X50 rxns
EUR 1211

Seamless cloning Master Mix (Kit)

B632219 40RXN, 40prep
EUR 266.63
  • Product category: Molecular Biology Kits/Cloning/Cloning Kits (Flexible)

Taq 2x PCR Mix 100 rxn

BA01501 100rxn
EUR 94
Description: High quality Taq polymerase for different PCR variations and downstream applications.

Taq 5x PCR Mix 12.5 mM

BT10402 250rxn
EUR 109
Description: High quality Taq polymerase for different PCR variations and downstream applications.

2x SYBR Green qPCR Master Mix

B21202 5 mL
EUR 224
Description: Our 2x SYBR Green qPCR master mix performs toe to toe in all qPCR assays with the most well known brands on the market but surpases them significantly in cost-efficiency.

2x SYBR Green qPCR Master Mix

B21203 25 mL
EUR 856
Description: Our 2x SYBR Green qPCR master mix performs toe to toe in all qPCR assays with the most well known brands on the market but surpases them significantly in cost-efficiency.

Fast Probe Master Mix (200 rxn)

31005 2x1ML
EUR 234
Description: Minimum order quantity: 1 unit of 2x1ML

Fast Probe Master Mix (500 rxn)

31005-1 5x1ML
EUR 466
Description: Minimum order quantity: 1 unit of 5x1ML

Fast Probe Master Mix (5000 rxn)

31005-2 50x1ML
EUR 3871
Description: Minimum order quantity: 1 unit of 50x1ML

Pfu 2x Master Mix - 200 Reactions

3326 1/EA
EUR 300

2 × AceTaq Master Mix (Dye Plus)

P412-01 1 ml
EUR 119

2 × AceTaq Master Mix (Dye Plus)

P412-02 5 ml
EUR 158

2 × AceTaq Master Mix (Dye Plus)

P412-03 15 ml
EUR 262

amfiSure ONE PCR Master Mix(2X)

P7000-005 5x1 ml
EUR 219

amfiSure ONE PCR Master Mix(2X)

P7000-010 10x1 ml
EUR 317

amfiSure ONE PCR Master Mix(2X)

P7000-050 50x1 ml
EUR 1211

amfiSure ONE PCR Master Mix(2X)

P7000-100 100x1 ml
EUR 2102

Maximo Dry-Master Mix (Lyophilized Polymerase)

S295 192 rcs (20µl, in plates or tubes)
EUR 133

AceQ Universal SYBR qPCR Master Mix

Q511-02 500 rxn (20 μl/rxn)
EUR 221

AceQ Universal SYBR qPCR Master Mix

Q511-03 2500 rxn (20 μl/rxn)
EUR 646

ChamQ Universal SYBR qPCR Master Mix

Q711-02 500 rxn (20 μl/rxn)
EUR 221

ChamQ Universal SYBR qPCR Master Mix

Q711-03 2500 rxn (20 μl/rxn)
EUR 646

ChamQ Geno-SNP Probe Master Mix

Q811-02 500 rxn (20 μl/rxn)
EUR 277

ChamQ Geno-SNP Probe Master Mix

Q811-03 2500 rxn (20 μl/rxn)
EUR 923

amfiRivert II cDNA Synthesis Master Mix

R5500-050 50 rxns
EUR 374

amfiRivert II cDNA Synthesis Master Mix

R5500-100 2x50rxns
EUR 577

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