
Prediction of Radioresistant Prostate Most cancers Based mostly on Differentially Expressed Proteins
Introduction:
Though relapses after radiotherapy are widespread in prostate most cancers (PCA) sufferers, these with a excessive threat for radioresistance can’t be recognized previous to therapy but. Subsequently, this proof-of-concept research was carried out to check protein expression profiles of sufferers with radio-recurrent PCA to sufferers handled with major radical prostatectomy separated by Gleason threat teams. We hypothesized that radio-recurrent PCA have an analogous protein expression as high-risk Gleason PCA.
Strategies:
Affected person cohorts consisted of (i) 31 sufferers handled with salvage prostatectomy for regionally recurrent PCA after major radiotherapy and (ii) 94 sufferers handled with major prostatectomy break up right into a Gleason high-risk (≥4 + 3; n = 42 [44.7%]) versus a low-risk group (≤3 + 4; n = 52 [55.3%]). Immunohistochemistry was carried out utilizing 15 antibodies with identified affiliation to radioresistance in PCA in vitro. ELISA was used for validation of chosen markers in serum.
Outcomes:
Androgen receptor (AR) was overexpressed in most radio-recurrent PCA (89.7%) and in most major high-risk Gleason PCA (87.8%; p = 0.851), whereas solely 67.3% of the low-risk group confirmed an expression (p = 0.017). Contemplating the best Gleason sample in major PCA, aldo-keto reductase household 1 member C3 (AKR1C3) was most equally expressed by sufferers with radio-recurrent PCA and sufferers with Gleason patterns Four and 5 (p = 0.827 and p = 0.893) in comparison with Gleason sample 3 (p = 0.20). These findings had been supported by ELISA.
Conclusion:
That is the primary research to judge protein markers with a purpose to predict radioresistance in PCA. Our outcomes level to AR and AKR1C3 as essentially the most promising markers which may assist stratify sufferers for radiotherapy.

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EHC0240 | Abclonal | 96Tests | EUR 521.00 |
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HGB-15 | CORNING | 1/pk | EUR 486.00 |
Description: Lab Equipment; Axygen Branded EQ |
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GFL-15 | Creative Diagnostics | 1 mL | EUR 1053.00 |
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HGB15-15-GT | CORNING | 1/pk | EUR 79.00 |
Description: Lab Equipment; Axygen Branded EQ |
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GPK-15 | Creative Diagnostics | 1 kit | EUR 715.00 |
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DB173RTU-15 | DB Biotech | 15 ml | EUR 355.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB174RTU-15 | DB Biotech | 15 ml | EUR 355.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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EGTC0240 | Abclonal | 96Tests | EUR 521.00 |
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ECC0240 | Abclonal | 96Tests | EUR 521.00 |
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ECKC0240 | Abclonal | 96Tests | EUR 521.00 |
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EBC0240 | Abclonal | 96Tests | EUR 521.00 |
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EAC0240 | Abclonal | 96Tests | EUR 521.00 |
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EPC0240 | Abclonal | 96Tests | EUR 521.00 |
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ERC0240 | Abclonal | 96Tests | EUR 521.00 |
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ERTC0240 | Abclonal | 96Tests | EUR 521.00 |
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ESC0240 | Abclonal | 96Tests | EUR 521.00 |
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EMC0240 | Abclonal | 96Tests | EUR 521.00 |
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EMKC0240 | Abclonal | 96Tests | EUR 521.00 |
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DB037RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB038RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB039RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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EGC0240 | Abclonal | 96Tests | EUR 521.00 |
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GST-ANTI-1 | Detroit R&D | 50 uL | EUR 280.00 |
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GST-ANTI-2 | Detroit R&D | 50 uL | EUR 280.00 |
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GST-ANTI-3 | Detroit R&D | 50 uL | EUR 280.00 |
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DB003RTU-15 | DB Biotech | 15 ml | EUR 428.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB026RTU-15 | DB Biotech | 15 ml | EUR 338.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB027RTU-15 | DB Biotech | 15 ml | EUR 414.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB041RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB042RTU-15 | DB Biotech | 15 ml | EUR 338.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB045RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB049RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB057RTU-15 | DB Biotech | 15 ml | EUR 414.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB062RTU-15 | DB Biotech | 15 ml | EUR 338.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB071RTU-15 | DB Biotech | 15 ml | EUR 414.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB082RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB085RTU-15 | DB Biotech | 15 ml | EUR 414.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB092RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB114RTU-15 | DB Biotech | 15 ml | EUR 428.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB115RTU-15 | DB Biotech | 15 ml | EUR 400.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB134RTU-15 | DB Biotech | 15 ml | EUR 347.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB135RTU-15 | DB Biotech | 15 ml | EUR 429.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB148RTU-15 | DB Biotech | 15 ml | EUR 347.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB151RTU-15 | DB Biotech | 15 ml | EUR 347.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB152RTU-15 | DB Biotech | 15 ml | EUR 347.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB156RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB159RTU-15 | DB Biotech | 15 ml | EUR 709.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB203RTU-15 | DB Biotech | 15 ml | EUR 347.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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YF-PA12886 | Abfrontier | 100 ul | EUR 403.00 |
Description: Rabbit polyclonal to Cytokeratin 15 |
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YF-PA12887 | Abfrontier | 100 ug | EUR 403.00 |
Description: Rabbit polyclonal to Cytokeratin 15 |
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YF-PA24745 | Abfrontier | 50 ul | EUR 334.00 |
Description: Mouse polyclonal to Calpain 15 |
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YF-PA18066 | Abfrontier | 50 ug | EUR 363.00 |
Description: Mouse polyclonal to Claudin 15 |
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YF-PA18067 | Abfrontier | 100 ug | EUR 403.00 |
Description: Rabbit polyclonal to Claudin 15 |
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YF-PA19752 | Abfrontier | 50 ul | EUR 363.00 |
Description: Mouse polyclonal to Kallikrein 15 |
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GFL-15-CU | Creative Diagnostics | 1mL | EUR 1365.00 |
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GCK-M-15 | Creative Diagnostics | 1 kit | EUR 757.00 |
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STJ16100371 | St John's Laboratory | 1 mL | EUR 956.00 |
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DB001RTU-15 | DB Biotech | 15 ml | EUR 265.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB050RTU-15 | DB Biotech | 15 ml | EUR 302.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB051RTU-15 | DB Biotech | 15 ml | EUR 309.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB055RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB066RTU-15 | DB Biotech | 15 ml | EUR 414.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB070RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB089RTU-15 | DB Biotech | 15 ml | EUR 428.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB098RTU-15 | DB Biotech | 15 ml | EUR 309.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB099RTU-15 | DB Biotech | 15 ml | EUR 302.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB100RTU-15 | DB Biotech | 15 ml | EUR 302.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB101RTU-15 | DB Biotech | 15 ml | EUR 302.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB102RTU-15 | DB Biotech | 15 ml | EUR 265.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB103RTU-15 | DB Biotech | 15 ml | EUR 265.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB106RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB107RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB111RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB119RTU-15 | DB Biotech | 15 ml | EUR 309.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() |
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DB158RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB208RTU-15 | DB Biotech | 15 ml | EUR 340.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB053RTU-15 | DB Biotech | 15 ml | EUR 406.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() |
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DB059RTU-15 | DB Biotech | 15 ml | EUR 428.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB060RTU-15 | DB Biotech | 15 ml | EUR 428.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB061RTU-15 | DB Biotech | 15 ml | EUR 428.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB097RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() |
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DB108RTU-15 | DB Biotech | 15 ml | EUR 428.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() |
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DB109RTU-15 | DB Biotech | 15 ml | EUR 428.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB253RTU-15 | DB Biotech | 15 ml | EUR 347.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() |
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DB047RTU-15 | DB Biotech | 15 ml | EUR 265.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() |
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DB048RTU-15 | DB Biotech | 15 ml | EUR 265.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB147RTU-15 | DB Biotech | 15 ml | EUR 347.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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FNab02198 | FN Test | 100µg | EUR 505.25 |
|
|||
Description: Antibody raised against Cytokeratin 15 |
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FNab02199 | FN Test | 100µg | EUR 548.75 |
|
|||
Description: Antibody raised against Cytokeratin 15 |
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A06396 | BosterBio | 100ul | EUR 397.00 |
Description: Rabbit Polyclonal MMP-15 Antibody. Validated in WB and tested in Human, Mouse. |
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A12099 | BosterBio | 100ul | EUR 397.00 |
Description: Rabbit Polyclonal Antibody for DHHC-15 Antibody (ZDHHC15) detection. Tested with WB in Human. |
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A06791 | BosterBio | 100ul | EUR 397.00 |
Description: Rabbit Polyclonal Antibody for Cytokeratin 15 Antibody (KRT15) detection.tested for WB in Human, Mouse, Rat, Monkey. |
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PAab02198 | Lifescience Market | 100 ug | EUR 355.00 |
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LF-PA20070 | Abfrontier | 100 ul | EUR 334.00 |
Description: Rabbit polyclonal to CDC2 |
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LF-PA20219 | Abfrontier | 100 ul | EUR 334.00 |
Description: Rabbit polyclonal to HSP27 |
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LF-PA20358 | Abfrontier | 100 ul | EUR 334.00 |
Description: Rabbit polyclonal to p53 |
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STJ92628 | St John's Laboratory | 200 µl | EUR 197.00 |
Description: Rabbit polyclonal to Cytokeratin 15. |
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STJ92707 | St John's Laboratory | 200 µl | EUR 197.00 |
Description: Rabbit polyclonal to DHHC-15. |
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STJ93253 | St John's Laboratory | 200 µl | EUR 197.00 |
Description: Rabbit polyclonal to GDF-15. |
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STJ94276 | St John's Laboratory | 200 µl | EUR 197.00 |
Description: Rabbit polyclonal to MMP-15. |
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STJ95018 | St John's Laboratory | 200 µl | EUR 197.00 |
Description: Rabbit polyclonal to PEA-15. |
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STJ95019 | St John's Laboratory | 200 µl | EUR 197.00 |
Description: Rabbit polyclonal to PEA-15. |
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STJ95020 | St John's Laboratory | 200 µl | EUR 197.00 |
Description: Rabbit polyclonal to PEA-15. |
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STJ97345 | St John's Laboratory | 200 µl | EUR 197.00 |
Description: Rabbit polyclonal to BMP-15. |
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STJ97982 | St John's Laboratory | 100 µl | EUR 234.00 |
Description: Mouse monoclonal to Cytokeratin 15. |
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STJ99006 | St John's Laboratory | 200 µl | EUR 197.00 |
Description: Rabbit polyclonal to IL-15. |
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STJ16100370 | St John's Laboratory | 1 mL | EUR 813.00 |
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STJ180109 | St John's Laboratory | 0.1 ml | EUR 213.00 |
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STJ180290 | St John's Laboratory | 0.1 ml | EUR 212.00 |
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STJ190030 | St John's Laboratory | 200 µl | EUR 197.00 |
Description: Unconjugated Mouse monoclonal to CK-15 (5A1) |
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YF-MA15522 | Abfrontier | 100 ug | EUR 363.00 |
Description: Mouse monoclonal to Calpain 15 |
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YF-MA15523 | Abfrontier | 100 ug | EUR 363.00 |
Description: Mouse monoclonal to Calpain 15 |
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YF-PA10168 | Abfrontier | 100 ug | EUR 403.00 |
Description: Rabbit polyclonal to 15 Lipoxygenase 1 |
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YF-PA18816 | Abfrontier | 50 ul | EUR 363.00 |
Description: Mouse polyclonal to Protease Inhibitor 15 |
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A2038-100 | Biovision | 100 µl | EUR 419.00 |
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STS-15-50 | Alpha Diagnostics | 1 Pk | Ask for price |
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STSD-15-50 | Alpha Diagnostics | 1 Pk | Ask for price |
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DB-173-RTU-15 | DB Biotech | 15 ml | EUR 355.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() |
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DB-174-RTU-15 | DB Biotech | 15 ml | EUR 355.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() |
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DB094RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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RC212-26 | Bio Basic | 2ug | EUR 104.38 |
|
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A1278-15 | Biovision | 15 ml | EUR 322.00 |
|
|||
Description: Goat IgG Secondary antibody Clone: pAb against UltraPolymer Goat Anti-Human IgG (H&L) HRPfor application in IHC.The immunogen is Human IgG (H&L).This antibody can be used for detection of the target molecule in samples from Human. |
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A1274-15 | Biovision | EUR 321.00 |
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A1275-15 | Biovision | EUR 321.00 |
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A1276-15 | Biovision | EUR 321.00 |
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A1277-15 | Biovision | EUR 338.00 |
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A1279-15 | Biovision | EUR 321.00 |
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DB211-RTU-15 | DB Biotech | 15 ml | EUR 355.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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DB213-RTU-15 | DB Biotech | 15 ml | EUR 355.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() |
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DB216-RTU-15 | DB Biotech | 15 ml | EUR 355.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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HGB15-10-15 | CORNING | 1/pk | EUR 60.00 |
Description: Lab Equipment; Axygen Branded EQ |
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HGB15-12-15 | CORNING | 1/pk | EUR 60.00 |
Description: Lab Equipment; Axygen Branded EQ |
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HGB15-20-15 | CORNING | 1/pk | EUR 60.00 |
Description: Lab Equipment; Axygen Branded EQ |
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HGB15-35-15 | CORNING | 1/pk | EUR 69.00 |
Description: Lab Equipment; Axygen Branded EQ |
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HGB15-8-15 | CORNING | 1/pk | EUR 69.00 |
Description: Lab Equipment; Axygen Branded EQ |
![]() |
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A1280-15 | Biovision | EUR 321.00 |
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M06819-15 | BosterBio | 100ug | EUR 468.00 |
Description: Anti-Dimethyl Histone H3 (Lys14) Rabbit Monoclonal Antibody, Clone#RM165 tested in WB, ELISA, Multiplex, reactive to All Vertebrates |
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AB-11510 | Alpha Diagnostics | 100 ug | EUR 347.00 |
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CPBT-65643RH | Creative Diagnostics | 0.1 mg | EUR 881.00 |
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FNab00005 | FN Test | 100µg | EUR 505.25 |
|
|||
Description: Antibody raised against 15 Lipoxygenase 2 |
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FNab03381 | FN Test | 100µg | EUR 585.00 |
|
|||
Description: Antibody raised against GCDFP-15/PIP |
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A00209 | BosterBio | 100ul | EUR 397.00 |
Description: Rabbit Polyclonal CDC2 (Ab-15) Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat. |
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A06791-1 | BosterBio | 100ul | EUR 397.00 |
Description: Mouse Monoclonal Antibody for Cytokeratin 15 Antibody (KRT15) detection.tested for Flow Cytometry, IF, IHC, WB in Human. |
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PAab00005 | Lifescience Market | 100 ug | EUR 355.00 |
![]() |
|||
PAab03381 | Lifescience Market | 100 ug | EUR 412.00 |
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|||
LF-PA20485 | Abfrontier | 100 ul | EUR 334.00 |
Description: Rabbit polyclonal to Stathmin 1 |
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|||
STJ93680 | St John's Laboratory | 200 µl | EUR 197.00 |
Description: Rabbit polyclonal to IL-15Ralpha. |
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|||
YF-MA11488 | Abfrontier | 100 ug | EUR 363.00 |
Description: Mouse monoclonal to Protease Inhibitor 15 |
![]() |
|||
YF-MA11900 | Abfrontier | 100 ug | EUR 363.00 |
Description: Mouse monoclonal to 15 Lipoxygenase 1 |
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|||
YF-MA11901 | Abfrontier | 100 ug | EUR 363.00 |
Description: Mouse monoclonal to 15 Lipoxygenase 2 |
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|||
YF-MA10038 | Abfrontier | 100 ug | EUR 363.00 |
Description: Mouse monoclonal to 15 Lipoxygenase 1 |
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|||
15 | Biobase | 96T/Box | Ask for price |
|
|||
Description: ELISA based test for quantitative detection of T3 (Triiodothyronine) |
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|||
DB241-RTU-15 | DB Biotech | 15 ml | EUR 678.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
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|||
C016-10ug | Novoprotein | 10ug | EUR 202.00 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0. |
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C016-1mg | Novoprotein | 1mg | EUR 1836.00 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0. |
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C016-500ug | Novoprotein | 500ug | EUR 1298.00 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0. |
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C016-50ug | Novoprotein | 50ug | EUR 496.00 |
Description: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.0. |
![]() |
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30145-05111 | AssayPro | 150 ug | EUR 261.00 |
![]() |
|||
DB-037-RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() |
|||
DB-038-RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() |
|||
DB-039-RTU-15 | DB Biotech | 15 ml | EUR 354.00 |
Description: rabbit monospecific clonal antibodies for ihc-p application; prediluted (ready to use) |
![]() |
|||
HGB15-14MC-15 | CORNING | 1/pk | EUR 63.00 |
Description: Lab Equipment; Axygen Branded EQ |
![]() |
|||
HGB15-16MC-15 | CORNING | 1/pk | EUR 60.00 |
Description: Lab Equipment; Axygen Branded EQ |
![]() |
|||
HGB15-18MC-15 | CORNING | 1/pk | EUR 60.00 |
Description: Lab Equipment; Axygen Branded EQ |
![]() |
|||
HGB15-28MC-15 | CORNING | 1/pk | EUR 62.00 |
Description: Lab Equipment; Axygen Branded EQ |
![]() |
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HGB15-30MC-15 | CORNING | 1/pk | EUR 62.00 |
Description: Lab Equipment; Axygen Branded EQ |
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EH0177 | FN Test | 96T | EUR 476.25 |
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Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 9.375pg/ml |
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GA-E0137HM-48T | GenAsia Biotech | 48T | EUR 289.00 |
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GA-E0137HM-96T | GenAsia Biotech | 96T | EUR 466.00 |
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abx195854-96tests | Abbexa | 96 tests | EUR 825.00 |
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201-12-0098 | SunredBio | 96 tests | EUR 440.00 |
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Description: A quantitative ELISA kit for measuring Human in samples from biological fluids. |
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CSB-E04603h-24T | Cusabio | 1 plate of 24 wells | EUR 165.00 |
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Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 15, IL-15 in samples from serum, plasma, tissue homogenates, cell culture supernates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price. |
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1-CSB-E04603h | Cusabio |
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Description: Quantitativesandwich ELISA kit for measuring Human Interleukin 15, IL-15 in samples from serum, plasma, tissue homogenates, cell culture supernates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits. |
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CN-03216H1 | ChemNorm | 96T | EUR 434.00 |
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CN-03216H2 | ChemNorm | 48T | EUR 284.00 |
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LF-EK60041 | Abfrontier | 1×96T | EUR 790.00 |
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QY-E04325 | Qayee Biotechnology | 96T | EUR 361.00 |
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PROTP40933 | BosterBio | Regular: 10ug | EUR 317.00 |
Description: Interleukin-15 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 114 amino acids (and an N-terminal Methionine) and having a molecular mass of 12.8kDa. The IL-15 is purified by proprietary chromatographic techniques. |
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HY-P7034 | MedChemExpress | 50ug | EUR 670.00 |
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NB312M-15 | Innovex | 15 ml | EUR 427.00 |
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NB312T-15 | Innovex | 15 ml | EUR 427.00 |
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PB9073 | BosterBio | 100ug/vial | EUR 334.00 |
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MA1116 | BosterBio | 100ug/vial | EUR 334.00 |
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M06791-1 | BosterBio | 100ug/vial | EUR 397.00 |
Description: Rabbit Monoclonal Cytokeratin 15 Antibody. Validated in IF, WB and tested in Human, Mouse. |
The ribotoxin-like protein Ostreatin from Pleurotus ostreatus fruiting our bodies: Affirmation of a novel ribonuclease household expressed in basidiomycetes
Fungi produce a number of toxins energetic towards crops, animal or people. Amongst them, ribotoxins are enzymes that particularly assault ribosomes irreparably compromising protein synthesis, helpful as pesticides or as anticancer brokers. Right here, a novel ribotoxin from the edible mushroom Pleurotus ostreatus has been purified and characterised.
This ribotoxin, named Ostreatin, is a particular ribonuclease releasing α-fragment when incubated with yeast or rabbit ribosomes. Ostreatin exhibits IC50 of 234 pM in rabbit reticulocyte lysate, and metallic dependent endonuclease exercise. Following the completion of Ostreatin major construction, we ascertained that this toxin is homologous to Ageritin, the primary ribotoxin-like protein from the basidiomycete Agrocybe aegerita, with which it shares 38.8% amino acid sequence identification.
Ostreatin consists of 131 amino acid residues with an experimental molecular mass of 14,263.51 Da ([M+H+]+). Homology modeling revealed that Ostreatin and Ageritin share an analogous fold by which the widespread catalytic triad is conserved.
Purified Ostreatin lacks N-terminal and C-terminal peptides, which as an alternative are current within the Ostreatin coding sequence. Such peptides are in all probability concerned in protein sorting and for this they might be eliminated. Our findings affirm the presence of ribotoxin-like proteins in basidiomycetes edible mushrooms, that we suggest as novel instrument for biotechnological functions.
Characterization of differentially expressed plasma proteins in sufferers with acute myocardial infarction
Acute myocardial infarction (AMI) stays a number one reason for morbidity and mortality worldwide. Novel biomarkers are wanted to establish NSTEMI in AMI sufferers. The research goal was to make use of proteomics to establish novel plasma biomarkers for STEMI and NSTEMI sufferers. iTRAQ evaluation was carried out on pooled samples from Eight wholesome controls and 12 STEMI and 12 NSTEMI sufferers.
Bioinformatics evaluation recognized 95 differentially expressed proteins that had been differentially expressed within the plasma of AMI sufferers and wholesome controls; 28 of those proteins had been present in STEMI/Con (22 upregulated and 6 downregulated), 48 in NSTEMI/Con (12 upregulated and 36 downregulated), and 44 in NSTEMI/STEMI (11 upregulated and 33 downregulated). Protein community evaluation was then carried out utilizing STRING software program.
Practical evaluation revealed that the recognized plasma proteins had been primarily concerned with carbon metabolism, toll-like receptor signaling pathway, and hypertrophic cardiomyopathy. 9 of the proteins (SSA1, MDH1, FCN2, GPI, S100A8, LBP, vinculin, VDBP, and RBP4) that modified ranges throughout AMI development had been additional validated by ELISA. The constructed plasma proteome may mirror the AMI pathogenesis molecular mechanisms and supply a technique for the early identification of NSTEMI in AMI sufferers. SIGNIFICANCE:
The goal of this research was to make use of proteomics to establish novel predictive plasma biomarkers for sufferers with acute myocardial infarction (AMI), which might enable for both identification of people liable to an infarction, and early identification of NSTEMI in sufferers with AMI. Utilizing an strategy that mixed iTRAQ with LC-MS/MS, we discovered 95 proteins that confirmed vital variations in expression ranges among the many AMI sufferers and wholesome controls.
The proteins SSA1, MDH1, FCN2, GPI, S100A8, LBP, vinculin, VDBP, and RBP4 had been discovered to play essential roles within the pathogenesis of AMI. Utilizing bioinformatics evaluation, we discovered that dysregulation of carbon metabolism, toll-like receptor signaling pathway, and hypertrophic cardiomyopathy would be the main driving forces for cardiac harm throughout myocardial infarction.
Nonetheless, additional investigations are wanted to confirm the mechanisms concerned within the improvement of AMI particularly NSTEMI. Taken collectively, our findings lay the muse for understanding the molecular mechanisms underlying the pathogenic processes of AMI, and recommend potential functions for particular biomarkers in early prognosis and willpower of prognosis.
![]() 2 × Taq Master Mix |
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P111-02 | Vazyme | 15 ml | EUR 146.00 |
![]() 2 × Taq Master Mix |
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P111-03 | Vazyme | 50 ml | EUR 236.00 |
![]() Accuris Taq Master Mix |
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PR1001-1000 | BenchMark | 1 PC | EUR 300.26 |
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![]() Accuris Taq Master Mix |
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PR1001-200 | BenchMark | 1 PC | EUR 121.62 |
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![]() Accuris Taq Master Mix |
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PR1001-S | BenchMark | 1 PC | EUR 69.79 |
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![]() 2 × Taq Plus Master Mix |
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P211-01 | Vazyme | 5 ml | EUR 134.00 |
![]() 2 × Taq Plus Master Mix |
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P211-02 | Vazyme | 15 ml | EUR 193.00 |
![]() 2 × Taq Plus Master Mix |
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P211-03 | Vazyme | 50 ml | EUR 389.00 |
![]() 2 × Rapid Taq Master Mix |
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P222-01 | Vazyme | 5 ml (5×1ml) | EUR 120.00 |
![]() 2 × Rapid Taq Master Mix |
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P222-02 | Vazyme | 15 ml (15×1ml) | EUR 153.00 |
![]() 2 × Rapid Taq Master Mix |
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P222-03 | Vazyme | 50 ml (50 x 1 ml) | EUR 257.00 |
![]() 2 × Rapid Taq Master Mix |
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P222-04 | Vazyme | 50 ml (10×5ml) | EUR 257.00 |
![]() Accuris Taq Plus Master Mix |
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PR1001-TP-1000 | BenchMark | 1 PC | EUR 827.41 |
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![]() Accuris Taq Plus Master Mix |
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PR1001-TP-200 | BenchMark | 1 PC | EUR 242.84 |
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![]() Accuris Taq Plus Master Mix |
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PR1001-TP-S | BenchMark | 1 PC | EUR 69.79 |
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![]() 2× EpiArt HS Taq Master Mix |
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EM201-01 | Vazyme | 1ml | EUR 145.00 |
![]() 2× EpiArt HS Taq Master Mix |
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EM201-02 | Vazyme | 5 ml (5×1ml) | EUR 303.00 |
![]() 2× EpiArt HS Taq Master Mix |
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EM201-03 | Vazyme | 15 ml (15×1ml) | EUR 642.00 |
![]() 2 × Taq Master Mix (Dye Plus) |
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P112-01 | Vazyme | 5 ml | EUR 117.00 |
![]() 2 × Taq Master Mix (Dye Plus) |
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P112-02 | Vazyme | 15 ml | EUR 146.00 |
![]() 2 × Taq Master Mix (Dye Plus) |
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P112-03 | Vazyme | 50 ml | EUR 236.00 |
![]() Accuris Hot Start Taq Master Mix |
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PR1001-HS-1000 | BenchMark | 1 PC | EUR 490.87 |
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![]() Accuris Hot Start Taq Master Mix |
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PR1001-HS-200 | BenchMark | 1 PC | EUR 169.47 |
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![]() Accuris Taq Master Mix Red Dye |
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PR1001-R-1000 | BenchMark | 1 PC | EUR 300.26 |
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![]() Accuris Taq Master Mix Red Dye |
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PR1001-R-200 | BenchMark | 1 PC | EUR 121.62 |
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![]() Accuris Taq Master Mix Red Dye |
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PR1001-R-S | BenchMark | 1 PC | EUR 69.79 |
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![]() 2×Taq PCR Master Mix(with dye) |
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K1034-1 | ApexBio | 1 ml | EUR 73.00 |
![]() 2×Taq PCR Master Mix(with dye) |
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K1034-100 | ApexBio | 100×1 ml | EUR 792.00 |
![]() 2×Taq PCR Master Mix(with dye) |
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K1034-20 | ApexBio | 20×1 ml | EUR 282.00 |
![]() 2×Taq PCR Master Mix(with dye) |
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K1034-5 | ApexBio | 5×1 ml | EUR 119.00 |
![]() 2×Taq PCR Master Mix(with dye) |
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K1034-50 | ApexBio | 50×1 ml | EUR 514.00 |
![]() 2 × Taq Plus Master Mix (Dye Plus) |
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P212-01 | Vazyme | 5 ml | EUR 133.00 |
![]() 2 × Taq Plus Master Mix (Dye Plus) |
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P212-02 | Vazyme | 15 ml | EUR 193.00 |
![]() 2 × Taq Plus Master Mix (Dye Plus) |
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P212-03 | Vazyme | 50 ml | EUR 389.00 |
![]() Taq PCR Master Mix (2X, Blue Dye) |
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BS9295 | Bio Basic | 1ml | EUR 84.80 |
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![]() Taq PCR Master Mix (2X, Blue Dye) |
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BS9296 | Bio Basic | 5ml | EUR 189.20 |
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![]() Taq PCR Master Mix (2X, Red Dye) |
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BS9297 | Bio Basic | 1ml | EUR 84.80 |
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![]() Taq PCR Master Mix (2X, Red Dye) |
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BS9298 | Bio Basic | 5ml | EUR 189.20 |
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![]() Hot Start Taq 2x Master Mix - 500 Reactions |
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3296 | Intact Genomics | 1/EA | EUR 268.00 |
![]() 2× EpiArt HS Taq Master Mix (Dye Plus) |
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EM202-01 | Vazyme | 1ml | EUR 145.00 |
![]() 2× EpiArt HS Taq Master Mix (Dye Plus) |
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EM202-02 | Vazyme | 5 ml (5×1ml) | EUR 303.00 |
![]() 2× EpiArt HS Taq Master Mix (Dye Plus) |
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EM202-03 | Vazyme | 15 ml (15×1ml) | EUR 642.00 |
![]() 2 × Taq Plus Master Mix II (Dye Plus) |
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P213-01 | Vazyme | 5 ml | EUR 134.00 |
![]() 2 × Taq Plus Master Mix II (Dye Plus) |
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P213-02 | Vazyme | 15 ml | EUR 193.00 |
![]() 2 × Taq Plus Master Mix II (Dye Plus) |
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P213-03 | Vazyme | 50 ml | EUR 389.00 |
![]() Accuris Hot Start Taq Master Mix Red Dye |
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PR1001-HSR-1000 | BenchMark | 1 PC | EUR 490.87 |
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![]() Accuris Hot Start Taq Master Mix Red Dye |
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PR1001-HSR-200 | BenchMark | 1 PC | EUR 169.47 |
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![]() Accuris Hot Start Taq Master Mix Red Dye |
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PR1001-HSR-S | BenchMark | 1 PC | EUR 69.79 |
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![]() Green Taq Mix |
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P131-01 | Vazyme | 5 ml | EUR 119.00 |
![]() Green Taq Mix |
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P131-02 | Vazyme | 15 ml | EUR 150.00 |
![]() Green Taq Mix |
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P131-03 | Vazyme | 50 ml | EUR 248.00 |
![]() Jade? Master Mix |
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M1105-500 | Biovision | EUR 441.00 |
![]() Taqman Master Mix |
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M1121-500 | Biovision | EUR 441.00 |
![]() 2 × AceTaq Master Mix |
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P411-01 | Vazyme | 1 ml | EUR 119.00 |
![]() 2 × AceTaq Master Mix |
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P411-02 | Vazyme | 5 ml | EUR 158.00 |
![]() 2 × AceTaq Master Mix |
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P411-03 | Vazyme | 15 ml | EUR 262.00 |
![]() amfiSure PCR Master Mix |
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P0311-010 | GenDepot | 2x50 rxns | EUR 126.00 |
![]() amfiSure PCR Master Mix |
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P0311-025 | GenDepot | 5X50 rxns | EUR 165.00 |
![]() amfiSure PCR Master Mix |
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P0311-050 | GenDepot | 10X50 rxns | EUR 219.00 |
![]() amfiSure PCR Master Mix |
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P0311-100 | GenDepot | 10x1ml | EUR 286.00 |
![]() amfiSure PCR Master Mix |
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P0311-125 | GenDepot | 15X50 rxns | EUR 278.00 |
![]() amfiSure PCR Master Mix |
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P0311-200 | GenDepot | 20x1ml | EUR 469.00 |
![]() amfiSure PCR Master Mix |
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P0311-250 | GenDepot | 50x50 rxns | EUR 752.00 |
![]() amfiSure PCR Master Mix |
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P0311-500 | GenDepot | 100x50 rxns | EUR 1258.00 |
![]() amfiXpand PCR Master Mix |
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P0331-010 | GenDepot | 2X50 rxns | EUR 151.00 |
![]() amfiXpand PCR Master Mix |
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P0331-025 | GenDepot | 5X50 rxns | EUR 273.00 |
![]() amfiXpand PCR Master Mix |
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P0331-050 | GenDepot | 10X50 rxns | EUR 448.00 |
![]() amfiXpand PCR Master Mix |
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P0331-250 | GenDepot | 50x50 rxns | EUR 1873.00 |
![]() Taqman Master Mix-iCycler |
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M1122-500 | Biovision | EUR 441.00 |
![]() Taqman Master Mix-ROX |
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M1124-500 | Biovision | EUR 441.00 |
![]() Taqman Master Mix-Multiplex |
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M1125-500 | Biovision | EUR 441.00 |
![]() SYBR Green qPCR Master Mix |
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HY-K0501 | MedChemExpress | 5 mL (500 rxns) | EUR 263.00 |
![]() RT Master Mix for qPCR |
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HY-K0510 | MedChemExpress | 1 mL (100 rxns) | EUR 291.00 |
![]() 2 × Phanta Max Master Mix |
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P515-01 | Vazyme | 1 ml | EUR 145.00 |
![]() 2 × Phanta Max Master Mix |
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P515-02 | Vazyme | 5 ml | EUR 269.00 |
![]() 2 × Phanta Max Master Mix |
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P515-03 | Vazyme | 15 ml | EUR 575.00 |
![]() amfiSure Prime PCR Master Mix |
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P1311-025 | GenDepot | 5X50 rxns | EUR 161.00 |
![]() amfiSure Prime PCR Master Mix |
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P1311-050 | GenDepot | 10X50 rxns | EUR 219.00 |
![]() amfiSure Prime PCR Master Mix |
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P1311-125 | GenDepot | 15X50 rxns | EUR 273.00 |
![]() amfiSure Prime PCR Master Mix |
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P1311-250 | GenDepot | 50x50 rxns | EUR 739.00 |
![]() amfiSure Prime PCR Master Mix |
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P1311-500 | GenDepot | 100x50 rxns | EUR 1238.00 |
![]() amfiSure Advanced PCR Master Mix |
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P2311-025 | GenDepot | 5X50 rxns | EUR 165.00 |
![]() amfiSure Advanced PCR Master Mix |
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P2311-050 | GenDepot | 10X50 rxns | EUR 223.00 |
![]() amfiSure Advanced PCR Master Mix |
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P2311-125 | GenDepot | 15X50 rxns | EUR 282.00 |
![]() amfiSure Advanced PCR Master Mix |
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P2311-250 | GenDepot | 50x50 rxns | EUR 752.00 |
![]() amfiSure Advanced PCR Master Mix |
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P2311-500 | GenDepot | 100x50 rxns | EUR 1279.00 |
![]() 2 × Vazyme LAmp Master Mix |
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P311-01 | Vazyme | 1 ml | EUR 137.00 |
![]() 2 × Vazyme LAmp Master Mix |
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P311-02 | Vazyme | 5 ml | EUR 212.00 |
![]() 2 × Vazyme LAmp Master Mix |
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P311-03 | Vazyme | 15 ml | EUR 401.00 |
![]() Taqman Master Mix-Low ROX |
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M1123-500 | Biovision | EUR 441.00 |
![]() amfiRivert cDNA Synthesis Master Mix |
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R5101-050 | GenDepot | 50 rxns | EUR 415.00 |
![]() amfiRivert cDNA Synthesis Master Mix |
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R5101-100 | GenDepot | 2X50 rxns | EUR 847.00 |
![]() amfiRivert cDNA Synthesis Master Mix |
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R5101-200 | GenDepot | 4X50 rxns | EUR 1211.00 |
![]() AceQ qPCR Probe Master Mix |
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Q112-02 | Vazyme | 500 rxn (20 μl/rxn) | EUR 221.00 |
![]() AceQ qPCR Probe Master Mix |
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Q112-03 | Vazyme | 2500 rxn (20 μl/rxn) | EUR 646.00 |
![]() AceQ U+ Probe Master Mix |
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Q113-02 | Vazyme | 500 rxn (20 μl/rxn) | EUR 267.00 |
![]() AceQ U+ Probe Master Mix |
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Q113-03 | Vazyme | 2500 rxn (20 μl/rxn) | EUR 842.00 |
![]() Seamless cloning Master Mix (Kit) |
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B632219 | Bio Basic | 40RXN, 40prep | EUR 266.63 |
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![]() Taq 5x PCR Mix 12.5 mM |
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BT10402 | Bioatlas | 250rxn | EUR 109.00 |
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
![]() Taq 2x PCR Mix 100 rxn |
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BA01501 | Bioatlas | 100rxn | EUR 94.00 |
Description: High quality Taq polymerase for different PCR variations and downstream applications. |
![]() Fast Probe Master Mix (200 rxn) |
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31005 | Biotium | 2x1ML | EUR 234.00 |
Description: Minimum order quantity: 1 unit of 2x1ML |
![]() Fast Probe Master Mix (500 rxn) |
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31005-1 | Biotium | 5x1ML | EUR 466.00 |
Description: Minimum order quantity: 1 unit of 5x1ML |
![]() Fast Probe Master Mix (5000 rxn) |
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31005-2 | Biotium | 50x1ML | EUR 3871.00 |
Description: Minimum order quantity: 1 unit of 50x1ML |
![]() Pfu 2x Master Mix - 200 Reactions |
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3326 | Intact Genomics | 1/EA | EUR 300.00 |
![]() 2x SYBR Green qPCR Master Mix |
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B21202 | Bimake | 5 mL | EUR 224.00 |
Description: Our 2x SYBR Green qPCR master mix performs toe to toe in all qPCR assays with the most well known brands on the market but surpases them significantly in cost-efficiency. |
![]() 2x SYBR Green qPCR Master Mix |
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B21203 | Bimake | 25 mL | EUR 856.00 |
Description: Our 2x SYBR Green qPCR master mix performs toe to toe in all qPCR assays with the most well known brands on the market but surpases them significantly in cost-efficiency. |
![]() 2 × AceTaq Master Mix (Dye Plus) |
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P412-01 | Vazyme | 1 ml | EUR 119.00 |
![]() 2 × AceTaq Master Mix (Dye Plus) |
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P412-02 | Vazyme | 5 ml | EUR 158.00 |
![]() 2 × AceTaq Master Mix (Dye Plus) |
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P412-03 | Vazyme | 15 ml | EUR 262.00 |
![]() amfiSure ONE PCR Master Mix(2X) |
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P7000-005 | GenDepot | 5x1 ml | EUR 219.00 |
![]() amfiSure ONE PCR Master Mix(2X) |
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P7000-010 | GenDepot | 10x1 ml | EUR 317.00 |
![]() amfiSure ONE PCR Master Mix(2X) |
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P7000-050 | GenDepot | 50x1 ml | EUR 1211.00 |
![]() amfiSure ONE PCR Master Mix(2X) |
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P7000-100 | GenDepot | 100x1 ml | EUR 2102.00 |
![]() amfiRivert II cDNA Synthesis Master Mix |
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R5500-050 | GenDepot | 50 rxns | EUR 374.00 |
![]() amfiRivert II cDNA Synthesis Master Mix |
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R5500-100 | GenDepot | 2x50rxns | EUR 577.00 |
![]() amfiRivert cDNA Synthesis Prime Master Mix |
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R5610-050 | GenDepot | 50 rxns | EUR 412.00 |
![]() amfiRivert cDNA Synthesis Prime Master Mix |
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R5610-100 | GenDepot | 2x50 rxns | EUR 671.00 |
![]() amfiRivert cDNA Synthesis Prime Master Mix |
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R5610-200 | GenDepot | 4X50 rxns | EUR 1211.00 |
![]() amfiRivert cDNA Synthesis Prime Master Mix |
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R5610-500 | GenDepot | 10x50 rxns | EUR 2548.00 |
![]() Maximo Dry-Master Mix (Lyophilized Polymerase) |
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S295 | GeneOn | 192 rcs (20µl, in plates or tubes) | EUR 133.00 |
![]() AceQ Universal SYBR qPCR Master Mix |
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Q511-02 | Vazyme | 500 rxn (20 μl/rxn) | EUR 221.00 |
![]() AceQ Universal SYBR qPCR Master Mix |
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Q511-03 | Vazyme | 2500 rxn (20 μl/rxn) | EUR 646.00 |